CFHR2

CFHR2
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesCFHR2, CFHL2, FHR2, HFL3, complement factor H related 2
External IDsHomoloGene: 130536 GeneCards: CFHR2
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1q31.3Start196,943,772 bp[1]
End196,959,226 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

3080

n/a

Ensembl

ENSG00000080910

n/a

UniProt

P36980

n/a

RefSeq (mRNA)

NM_001312672
NM_005666

n/a

RefSeq (protein)

NP_001299601
NP_005657

n/a

Location (UCSC)Chr 1: 196.94 – 196.96 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Complement factor H-related protein 2 is a protein that in humans is encoded by the CFHR2 gene.[3][4][5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000080910 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:".
  3. ↑ Skerka C, Timmann C, Horstmann RD, Zipfel PF (Jun 1992). "Two additional human serum proteins structurally related to complement factor H. Evidence for a family of factor H-related genes". J Immunol. 148 (10): 3313–8. PMID 1533657.
  4. ↑ Skerka C, Moulds JM, Taillon-Miller P, Hourcade D, Zipfel PF (Oct 1995). "The human factor H-related gene 2 (FHR2): structure and linkage to the coagulation factor XIIIb gene". Immunogenetics. 42 (4): 268–74. doi:10.1007/bf00176444. PMID 7672821.
  5. ↑ "Entrez Gene: CFHR2 complement factor H-related 2".

Further reading

  • Zipfel PF, Skerka C (1994). "Complement factor H and related proteins: an expanding family of complement-regulatory proteins?". Immunol. Today. 15 (3): 121–6. doi:10.1016/0167-5699(94)90155-4. PMID 8172644.
  • Hageman GS, Hancox LS, Taiber AJ, et al. (2007). "Extended Haplotypes in the Complement Factor H (CFH) and CFH-related (CFHR) Family of Genes that Protect against Age-related Macular Degeneration: Identification, Ethnic Distribution and Evolutionary Implications". Ann. Med. 38 (8): 592–604. doi:10.1080/07853890601097030. PMC 1905836. PMID 17438673.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Díaz-Guillén MA, Rodríguez de Córdoba S, Heine-Suñer D (1999). "A radiation hybrid map of complement factor H and factor H-related genes". Immunogenetics. 49 (6): 549–52. doi:10.1007/s002510050534. PMID 10380701.
  • Skerka C, Horstmann RD, Zipfel PF (1991). "Molecular cloning of a human serum protein structurally related to complement factor H". J. Biol. Chem. 266 (18): 12015–20. PMID 1711047.


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