CENPK

CENPK
Identifiers
Aliases	CENPK, AF5alpha, CENP-K, P33, Solt, FKSG14, centromere protein K
External IDs	MGI: 1926210 HomoloGene: 11035 GeneCards: CENPK
Gene location (Human)
Chr.	Chromosome 5 (human)[1]
End	65,563,171 bp[1]
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)[2]
End	104,252,392 bp[2]
Gene ontology
Molecular function	• protein binding;
Cellular component	• cytosol; • cell nucleus; • nucleoplasm; • condensed chromosome kinetochore; • chromosome, centromeric region; • chromosome; • kinetochore;
Biological process	• CENP-A containing nucleosome assembly; • kinetochore assembly;
	Sources:Amigo / QuickGO
Orthologs
	64105
	60411
	ENSG00000123219
	ENSMUSG00000021714
	Q9BS16
	Q9ESN5
	NM_001267038; NM_022145; NM_001349367; NM_001349368; NM_001349369
	NM_021790; NM_181061
	NP_001253967; NP_071428; NP_001336296; NP_001336297; NP_001336298
	NP_068562; NP_851406
	Wikidata
View/Edit Human	View/Edit Mouse

Centromere protein K is a protein that in humans is encoded by the CENPK gene.^[5]^[6]

Interactions

CENPK has been shown to interact with SOX6.^[7]

1 2 3 GRCh38: Ensembl release 89: ENSG00000123219 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021714 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Taki T, Hayashi Y, Taniwaki M, Seto M, Ueda R, Hanada R, Suzukawa K, Yokota J, Morishita K (Nov 1996). "Fusion of the MLL gene with two different genes, AF-6 and AF-5alpha, by a complex translocation involving chromosomes 5, 6, 8 and 11 in infant leukemia". Oncogene. 13 (10): 2121–30. PMID 8950979.
↑ "Entrez Gene: CENPK centromere protein K".
↑ Yamashita A, Ito M, Takamatsu N, Shiba T (Sep 2000). "Characterization of Solt, a novel SoxLZ/Sox6 binding protein expressed in adult mouse testis". FEBS Letters. 481 (2): 147–51. doi:10.1016/S0014-5793(00)01987-6. PMID 10996314.

Human CENPK genome location and CENPK gene details page in the UCSC Genome Browser.

Izuta H, Ikeno M, Suzuki N, Tomonaga T, Nozaki N, Obuse C, Kisu Y, Goshima N, Nomura F, Nomura N, Yoda K (Jun 2006). "Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells". Genes to Cells. 11 (6): 673–84. doi:10.1111/j.1365-2443.2006.00969.x. PMID 16716197.
Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR, Desai A, Fukagawa T (May 2006). "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres". Nature Cell Biology. 8 (5): 446–57. doi:10.1038/ncb1396. PMID 16622420.
Foltz DR, Jansen LE, Black BE, Bailey AO, Yates JR, Cleveland DW (May 2006). "The human CENP-A centromeric nucleosome-associated complex". Nature Cell Biology. 8 (5): 458–69. doi:10.1038/ncb1397. PMID 16622419.
Obuse C, Yang H, Nozaki N, Goto S, Okazaki T, Yoda K (Feb 2004). "Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase". Genes to Cells. 9 (2): 105–20. doi:10.1111/j.1365-2443.2004.00705.x. PMID 15009096.
Yamashita A, Ito M, Takamatsu N, Shiba T (Sep 2000). "Characterization of Solt, a novel SoxLZ/Sox6 binding protein expressed in adult mouse testis". FEBS Letters. 481 (2): 147–51. doi:10.1016/S0014-5793(00)01987-6. PMID 10996314.

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