CCAR1

CCAR1
Identifiers
AliasesCCAR1, cell division cycle and apoptosis regulator 1
External IDsMGI: 1914750 HomoloGene: 10086 GeneCards: CCAR1
Gene location (Human)
Chr.Chromosome 10 (human)[1]
Band10q21.3Start68,721,012 bp[1]
End68,792,377 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

55749

67500

Ensembl

ENSG00000060339

ENSMUSG00000020074

UniProt

Q8IX12

Q8CH18

RefSeq (mRNA)

NM_001282959
NM_001282960
NM_018237

NM_026201

RefSeq (protein)

NP_001269888
NP_001269889
NP_060707

NP_080477

Location (UCSC)Chr 10: 68.72 – 68.79 MbChr 10: 62.74 – 62.79 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cell division cycle and apoptosis regulator protein 1 is a protein that in humans is encoded by the CCAR1 gene.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000060339 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020074 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Rishi AK, Zhang L, Boyanapalli M, Wali A, Mohammad RM, Yu Y, Fontana JA, Hatfield JS, Dawson MI, Majumdar AP, Reichert U (Aug 2003). "Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437". J Biol Chem. 278 (35): 33422–35. doi:10.1074/jbc.M303173200. PMID 12816952.
  6. ↑ "Entrez Gene: CCAR1 cell division cycle and apoptosis regulator 1".

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.
  • McDonald ER, El-Deiry WS (2004). "Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth". Proc. Natl. Acad. Sci. U.S.A. 101 (16): 6170–5. doi:10.1073/pnas.0307459101. PMC 395941. PMID 15069192.
  • Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Rishi AK, Zhang L, Yu Y, et al. (2006). "Cell cycle- and apoptosis-regulatory protein-1 is involved in apoptosis signaling by epidermal growth factor receptor". J. Biol. Chem. 281 (19): 13188–98. doi:10.1074/jbc.M512279200. PMID 16543231.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
  • Zhang L, Levi E, Majumder P, et al. (2007). "Transactivator of transcription-tagged cell cycle and apoptosis regulatory protein-1 peptides suppress the growth of human breast cancer cells in vitro and in vivo". Mol. Cancer Ther. 6 (5): 1661–72. doi:10.1158/1535-7163.MCT-06-0653. PMID 17513614.


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