CANT1

CANT1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCANT1, DBQD, SCAN-1, SCAN1, SHAPY, DBQD1, calcium activated nucleotidase 1, EDM7
External IDsMGI: 1923275 HomoloGene: 69460 GeneCards: CANT1
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17q25.3Start78,991,717 bp[1]
End79,009,867 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

124583

76025

Ensembl

ENSG00000171302

ENSMUSG00000025575

UniProt

Q8WVQ1

Q8VCF1

RefSeq (mRNA)

NM_001159772
NM_001159773
NM_138793

NM_001025617
NM_001025618
NM_001267591
NM_001267592
NM_029502

RefSeq (protein)

NP_001153244
NP_001153245
NP_620148

NP_001020788
NP_001020789
NP_001254520
NP_001254521
NP_083778

Location (UCSC)Chr 17: 78.99 – 79.01 MbChr 11: 118.41 – 118.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CANT1 is a gene that encodes soluble calcium-activated nucleotidase 1, an enzyme, in humans.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000171302 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025575 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Failer BU, Braun N, Zimmermann H (Sep 2002). "Cloning, expression, and functional characterization of a Ca(2+)-dependent endoplasmic reticulum nucleoside diphosphatase". J Biol Chem. 277 (40): 36978–86. doi:10.1074/jbc.M201656200. PMID 12167635.
  6. ↑ "Entrez Gene: CANT1 calcium activated nucleotidase 1".

Further reading

  • Smith TM, Hicks-Berger CA, Kim S, Kirley TL (2002). "Cloning, expression, and characterization of a soluble calcium-activated nucleotidase, a human enzyme belonging to a new family of extracellular nucleotidases". Arch. Biochem. Biophys. 406 (1): 105–15. doi:10.1016/S0003-9861(02)00420-4. PMID 12234496.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Murphy DM, Ivanenkov VV, Kirley TL (2003). "Bacterial expression and characterization of a novel, soluble, calcium-binding, and calcium-activated human nucleotidase". Biochemistry. 42 (8): 2412–21. doi:10.1021/bi026763b. PMID 12600208.
  • Matsuda A, Suzuki Y, Honda G, et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways". Oncogene. 22 (21): 3307–18. doi:10.1038/sj.onc.1206406. PMID 12761501.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Dai J, Liu J, Deng Y, et al. (2004). "Structure and protein design of a human platelet function inhibitor". Cell. 116 (5): 649–59. doi:10.1016/S0092-8674(04)00172-2. PMID 15006348.
  • Yang M, Kirley TL (2004). "Site-directed mutagenesis of human soluble calcium-activated nucleotidase 1 (hSCAN-1): identification of residues essential for enzyme activity and the Ca(2+)-induced conformational change". Biochemistry. 43 (28): 9185–94. doi:10.1021/bi049565o. PMID 15248776.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.


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