Brian M. Hoffman

Brian M. Hoffman (born August 7, 1941 in Chicago) is an American bioinorganic and physical chemist.

Career

Hoffman is a graduate of Lane Tech High School in Chicago and then studied chemistry at the University of Chicago receiving a bachelor's degree in 1962 and at Caltech with a PhD in chemistry in 1966 under the direction of Harden M. McConnell. Hoffman was briefly a postdoctoral scholar with Alexander Rich at MIT. In 1967 he started his appointment at Northwestern University, where he has remained throughout his career.

Research and recognition

Using electron-nuclear double-resonance (ENDOR) spectroscopy, Hoffman has investigated many enzyme mechanism.[1] Subject of this work include nitric oxide synthase, cytochrome P450, nickel-iron hydrogenase, and nitrogenase.[2]

In 2012, he received the Joseph Chatt Award, in 2013 the F. A. Cotton Medal. He also received the Bruker Award[3] He is a member of the National Academy of Sciences (2006), the American Academy of Arts and Sciences (2002) and the American Association for the Advancement of Science (1983). He was Sloan Fellow.

References

  1. ↑ Hoffman BM (2003). "ENDOR of Metalloenzymes". Accounts of Chemical Research. 36 (7): 522–529. doi:10.1021/ar0202565.
  2. ↑ Hoffman BM, Lukoyanov D, Dean DR, Seefeldt LC (2013). "Nitrogenase: A Draft Mechanism". Accounts of Chemical Research. 46 (2): 587–595. doi:10.1021/ar300267m. PMC 3578145.
  3. ↑ http://www.rsc.org/Membership/Networking/InterestGroups/ESRSpectroscopy/Awards.asp
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