Bis-GMA

Bis-GMA (bisphenol A-glycidyl methacrylate) is a resin commonly used in dental sealants.[1][2]

History

Bis-GMA was incorporated into composite dental resins in the 1960s by Rafael Bowen.[3]

Safety

Concerns have been raised about the potential for bis-GMA to break down into or be contaminated with the related compound bisphenol A.[3] However, no negative health effects of bis-GMA use in dental resins have been found.[4][2]

Composition

Salivary esterases can slowly degrade bis-GMA-based sealants, forming Bis-HPPP.[5]

References

  1. ↑ "bis-GMA". PubChem. Retrieved 21 April 2017.
  2. 1 2 Ahovuo-Saloranta, A; Forss, H; Walsh, T; Hiiri, A; Nordblad, A; Mäkelä, M; Worthington, HV (28 March 2013). "Sealants for preventing dental decay in the permanent teeth". The Cochrane Database of Systematic Reviews (3): CD001830. PMID 23543512.
  3. 1 2 LaBauve JR, Long KN, Hack GD, Bashirelahi N (2012). "What every dentist should known about bisphenol A". General Dentistry. 60 (5). PMID 23032231.
  4. ↑ Soderholm KJ, Mariotti A (February 1999). "Bis-GMA–based resins in dentistry: are they safe?". The Journal of the American Dental Association. 130 (2): 201–209. doi:10.14219/jada.archive.1999.0169.
  5. ↑ Shokati, Babak; Tam, Laura Eva; Santerre, J. Paul; Finer, Yoav (2010). "Effect of salivary esterase on the integrity and fracture toughness of the dentin-resin interface". Journal of Biomedical Materials Research Part B: Applied Biomaterials: n/a–n/a. doi:10.1002/jbm.b.31645.
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