Bernd Pichler

Bernd Pichler (born 26 December 1969) is a German biomedical engineer and expert in preclinical and molecular imaging as well as in imaging technology. He has been a Full Professor since 2008 and is Chair of the Department of Preclinical Imaging and Radiopharmacy[1] as well as Director of the Werner Siemens Imaging Center at the University of Tübingen, Germany.[2]

Life

Pichler grew up in Pfaffenhofen an der Ilm in Bavaria. After completing his high school education, he studied electrical engineering and biomedical engineering at the Technical University of Munich, Germany. Following his degree, he worked as a PhD student at the Clinic for Nuclear Medicine at the Technical University of Munich and the Max Planck Institute for Physics (Werner Heisenberg Institute). After gaining his doctorate in 2001, he initially worked as a post-doctoral research fellow at the Clinic of Nuclear Medicine. He moved to the University of California, Davis, as an Assistance Research Engineer (equal to Assistant Research Professor) in March 2003 and worked in the department of biomedical engineering. He became Head of the Laboratory for Preclinical Imaging and Imaging Technology at the University of Tübingen in January 2005. He has been a Full Professor at the University of Tübingen since 2008 and also Chair of the Department of Preclinical Imaging and Radiopharmacy at the Clinic of Radiology, which is part of University Hospital Tübingen, since January 2011. His professorship is funded by the Werner Siemens Foundation, which has its headquarters in Switzerland.[3] 2014–2015 he was President of the European Society for Molecular Imaging (ESMI).[4]

Research

Pichler is primarily conducting research in the development of new imaging processes for fundamental pre-clinical research and clinical usage. He played a major role in the development of an imaging procedure which combines positron emission tomography (PET) and magnetic resonance tomography (MRT) in one device (PET/MR). The laboratory headed by Pichler primarily focuses on fundamental research into new diagnosis and treatment methods in the fields of oncology, neurology, cardiology and immunology. He is holder and applicant of many patents on integrated PET/MR scanners and radioactive tracers.

Awards

Advanced Grant from the European Research Council, 2012[5]

Publications

  • Schmitz, Jennifer; Schwab, Julian; Schwenck, Johannes; Chen, Qian; Quintanilla-Martinez, Leticia; Hahn, Markus; Wietek, Beate; Schwenzer, Nina; Staebler, Annette; Kohlhofer, Ursula; Aina, Olulanu H; Hubbard, Neil E; Reischl, Gerald; Borowsky, Alexander D; Brucker, Sara; Nikolaou, Konstantin; La Fougère, Christian; Cardiff, Robert D; Pichler, Bernd J; Schmid, Andreas M (2016). "Decoding Intratumoral Heterogeneity of Breast Cancer by Multiparametric In Vivo Imaging: A Translational Study". Cancer Research. 76 (18): 5512–22. doi:10.1158/0008-5472.CAN-15-0642. PMC 5414858. PMID 27466286.
  • Rolle, Anna-Maria; Hasenberg, Mike; Thornton, Christopher R; Solouk-Saran, Djamschid; Männ, Linda; Weski, Juliane; Maurer, Andreas; Fischer, Eliane; Spycher, Philipp R; Schibli, Roger; Boschetti, Frederic; Stegemann-Koniszewski, Sabine; Bruder, Dunja; Severin, Gregory W; Autenrieth, Stella E; Krappmann, Sven; Davies, Genna; Pichler, Bernd J; Gunzer, Matthias; Wiehr, Stefan (2016). "ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo". Proceedings of the National Academy of Sciences. 113 (8): E1026–33. doi:10.1073/pnas.1518836113. PMC 4776455. PMID 26787852.
  • Griessinger, Christoph M; Maurer, Andreas; Kesenheimer, Christian; Kehlbach, Rainer; Reischl, Gerald; Ehrlichmann, Walter; Bukala, Daniel; Harant, Maren; Cay, Funda; Brück, Jürgen; Nordin, Renate; Kohlhofer, Ursula; Rammensee, Hans-Georg; Quintanilla-Martinez, Leticia; Schaller, Martin; Röcken, Martin; Pichler, Bernd J; Kneilling, Manfred (2015). "64Cu antibody-targeting of the T-cell receptor and subsequent internalization enables in vivo tracking of lymphocytes by PET". Proceedings of the National Academy of Sciences. 112 (4): 1161–6. doi:10.1073/pnas.1418391112. PMC 4313850. PMID 25587131.
  • Maier, Florian C; Wehrl, Hans F; Schmid, Andreas M; Mannheim, Julia G; Wiehr, Stefan; Lerdkrai, Chommanad; Calaminus, Carsten; Stahlschmidt, Anke; Ye, Lan; Burnet, Michael; Stiller, Detlef; Sabri, Osama; Reischl, Gerald; Staufenbiel, Mathias; Garaschuk, Olga; Jucker, Mathias; Pichler, Bernd J (2014). "Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion". Nature Medicine. 20 (12): 1485–92. doi:10.1038/nm.3734. PMID 25384087.
  • Wehrl, Hans F; Hossain, Mosaddek; Lankes, Konrad; Liu, Chih-Chieh; Bezrukov, Ilja; Martirosian, Petros; Schick, Fritz; Reischl, Gerald; Pichler, Bernd J (2013). "Simultaneous PET-MRI reveals brain function in activated and resting state on metabolic, hemodynamic and multiple temporal scales". Nature Medicine. 19 (9): 1184–9. doi:10.1038/nm.3290. PMID 23975025.
  • Müller-Hermelink, Nele; Braumüller, Heidi; Pichler, Bernd; Wieder, Thomas; Mailhammer, Reinhard; Schaak, Katrin; Ghoreschi, Kamran; Yazdi, Amir; Haubner, Roland; Sander, Christian A; Mocikat, Ralph; Schwaiger, Markus; Förster, Irmgard; Huss, Ralph; Weber, Wolfgang A; Kneilling, Manfred; Röcken, Martin (2008). "TNFR1 Signaling and IFN-γ Signaling Determine whether T Cells Induce Tumor Dormancy or Promote Multistage Carcinogenesis". Cancer Cell. 13 (6): 507–18. doi:10.1016/j.ccr.2008.04.001. PMID 18538734.
  • Judenhofer, Martin S; Wehrl, Hans F; Newport, Danny F; Catana, Ciprian; Siegel, Stefan B; Becker, Markus; Thielscher, Axel; Kneilling, Manfred; Lichy, Matthias P; Eichner, Martin; Klingel, Karin; Reischl, Gerald; Widmaier, Stefan; Röcken, Martin; Nutt, Robert E; Machulla, Hans-Jürgen; Uludag, Kamil; Cherry, Simon R; Claussen, Claus D; Pichler, Bernd J (2008). "Simultaneous PET-MRI: A new approach for functional and morphological imaging". Nature Medicine. 14 (4): 459–65. doi:10.1038/nm1700. PMID 18376410.

References

  1. ↑ "Department of Preclinical Imaging and Radiopharmacy". Medizin.uni-tuebingen.de. Retrieved 2017-04-30.
  2. ↑ "Staff Member - Imaging Science Center". Isct.uni-tuebingen.de (in German). Retrieved 2017-04-30.
  3. ↑ "Curriculum Vitae" (PDF). Isct.uni-tuebingen.de. Retrieved 2017-04-30.
  4. ↑ "Bernd Pichler". E-smi.eu. Retrieved 2017-04-30.
  5. ↑ "ERC Advance Grant 2012" (PDF). Erc.europa.eu. Retrieved 2017-04-30.
  • "Werner Siemens Imaging Center - Imaging Science Center". Isct.uni-tuebingen.de. Retrieved 30 April 2017.
  • "Department of Preclinical Imaging and Radiopharmacy". Medizin.uni-tuebingen.de. Retrieved 30 April 2017.
  • "ArchivFullview-Press Releases - University Tübingen". Uni-tuebingen.de. Retrieved 30 April 2017.
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