Benzophenone synthase

benzophenone synthase
Identifiers
EC number 2.3.1.151
CAS number 175780-21-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a benzophenone synthase (EC 2.3.1.151) is an enzyme that catalyzes the chemical reaction

3 malonyl-CoA + 3-hydroxybenzoyl-CoA 4 CoA + 2,3',4,6-tetrahydroxybenzophenone + 3 CO2

Thus, the two substrates of this enzyme are malonyl-CoA and 3-hydroxybenzoyl-CoA, whereas its 3 products are CoA, 2,3',4,6-tetrahydroxybenzophenone, and CO2.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase.

References

    • Beerhues L (1996). "Benzophenone synthase from cultured cells of Centaurium erythraea". FEBS Lett. 383 (3): 264&ndash, 6. doi:10.1016/0014-5793(96)00265-7. PMID 8925910.


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