BRK1

BRK1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesBRK1, C3orf10, MDS027, hHBrk1, HSPC300, BRICK1, SCAR/WAVE actin nucleating complex subunit
External IDsMGI: 1915406 HomoloGene: 10210 GeneCards: BRK1
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3p25.3Start10,115,592 bp[1]
End10,127,190 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

55845

101314

Ensembl

ENSG00000254999

ENSMUSG00000033940

UniProt

Q8WUW1

Q91VR8

RefSeq (mRNA)

NM_018462

NM_133937

RefSeq (protein)

NP_060932

NP_598698

Location (UCSC)Chr 3: 10.12 – 10.13 MbChr 6: 113.6 – 113.62 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable protein BRICK1 is a protein that in humans is encoded by the C3orf10 gene.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000254999 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033940 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Maranchie JK, Afonso A, Albert PS, Kalyandrug S, Phillips JL, Zhou S, Peterson J, Ghadimi BM, Hurley K, Riss J, Vasselli JR, Ried T, Zbar B, Choyke P, Walther MM, Klausner RD, Linehan WM (Jan 2004). "Solid renal tumor severity in von Hippel Lindau disease is related to germline deletion length and location". Human Mutation. 23 (1): 40–6. doi:10.1002/humu.10302. PMID 14695531.
  6. ↑ "Entrez Gene: C3orf10 chromosome 3 open reading frame 10".

Further reading

  • Cascón A, Escobar B, Montero-Conde C, Rodríguez-Antona C, Ruiz-Llorente S, Osorio A, Mercadillo F, Letón R, Campos JM, García-Sagredo JM, Benítez J, Malumbres M, Robledo M (Jun 2007). "Loss of the actin regulator HSPC300 results in clear cell renal cell carcinoma protection in Von Hippel-Lindau patients". Human Mutation. 28 (6): 613–21. doi:10.1002/humu.20496. PMID 17311301.
  • Mayne M, Moffatt T, Kong H, McLaren PJ, Fowke KR, Becker KG, Namaka M, Schenck A, Bardoni B, Bernstein CN, Melanson M (Apr 2004). "CYFIP2 is highly abundant in CD4+ cells from multiple sclerosis patients and is involved in T cell adhesion". European Journal of Immunology. 34 (4): 1217–27. doi:10.1002/eji.200324726. PMID 15048733.
  • Eden S, Rohatgi R, Podtelejnikov AV, Mann M, Kirschner MW (Aug 2002). "Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck". Nature. 418 (6899): 790–3. doi:10.1038/nature00859. PMID 12181570.
  • Witke W, Podtelejnikov AV, Di Nardo A, Sutherland JD, Gurniak CB, Dotti C, Mann M (Feb 1998). "In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly". The EMBO Journal. 17 (4): 967–76. doi:10.1093/emboj/17.4.967. PMC 1170446. PMID 9463375.
  • Kitamura T, Kitamura Y, Yonezawa K, Totty NF, Gout I, Hara K, Waterfield MD, Sakaue M, Ogawa W, Kasuga M (Feb 1996). "Molecular cloning of p125Nap1, a protein that associates with an SH3 domain of Nck". Biochemical and Biophysical Research Communications. 219 (2): 509–14. doi:10.1006/bbrc.1996.0264. PMID 8605018.


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