BPI fold-containing family B member 2

BPIFB2
Identifiers
AliasesBPIFB2, BPIL1, C20orf184, LPLUNC2, RYSR, dJ726C3.2, BPI fold containing family B member 2
External IDsMGI: 1913807 HomoloGene: 11884 GeneCards: BPIFB2
Gene location (Human)
Chr.Chromosome 20 (human)[1]
Band20q11.21Start33,007,600 bp[1]
End33,023,709 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

80341

66557

Ensembl

ENSG00000078898

ENSMUSG00000027481

UniProt

Q8N4F0

Q8C1E1

RefSeq (mRNA)

NM_025227

NM_025631

RefSeq (protein)

NP_079503

NP_079907

Location (UCSC)Chr 20: 33.01 – 33.02 MbChr 2: 153.88 – 153.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

BPI fold-containing family B member 2 (BPIFB2) also known as bactericidal/permeability-increasing protein-like 1 (BPI-like 1) is a protein that in humans is encoded by the BPIFB2 gene.[5][6]

Function

This gene encodes a member of the lipid transfer/lipopolysaccharide binding protein (LT/LBP) gene family. It is highly expressed in hypertrophic tonsils. This gene and three other members of the LT/LBP gene family form a cluster on the long arm of chromosome 20.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000078898 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027481 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Mulero JJ, Boyle BJ, Bradley S, Bright JM, Nelken ST, Ho TT, Mize NK, Childs JD, Ballinger DG, Ford JE, Rupp F (Aug 2002). "Three new human members of the lipid transfer/lipopolysaccharide binding protein family (LT/LBP)". Immunogenetics. 54 (5): 293–300. doi:10.1007/s00251-002-0467-3. PMID 12185532.
  6. 1 2 "Entrez Gene: BPIL1 bactericidal/permeability-increasing protein-like 1".

Further reading

  • Bingle CD, Bingle L (2000). "Characterisation of the human plunc gene, a gene product with an upper airways and nasopharyngeal restricted expression pattern". Biochim. Biophys. Acta. 1493 (3): 363–7. doi:10.1016/S0167-4781(00)00196-2. PMID 11018263.
  • Bingle CD, Craven CJ (2003). "PLUNC: a novel family of candidate host defence proteins expressed in the upper airways and nasopharynx". Hum. Mol. Genet. 11 (8): 937–43. doi:10.1093/hmg/11.8.937. PMID 11971875.
  • Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
  • Ramachandran P, Boontheung P, Xie Y, et al. (2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry". J. Proteome Res. 5 (6): 1493–503. doi:10.1021/pr050492k. PMID 16740002.


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