Atlas of Genetics and Cytogenetics in Oncology and Haematology

Atlas of Genetics and Cytogenetics in Oncology and Haematology
Content
Description The Atlas is a peer reviewed on-line journal / encyclopedia / database in open access dealing with chromosomes, genes and cancers and the biology of normal and cancerous cells.
Data types
captured		 Annotation on chromosomes, genes and cancers
Organisms Human
Miscellaneous
Versioning Yes
Data release
frequency		 every week
Curation policy Yes – manual (over 10,000 pages) and automatic (30,000 pages). Full review articles vs automatic annotation.

The Atlas of Genetics and Cytogenetics in Oncology and Haematology, created in 1997 by Jean-Loup Huret (with bioinformatics by Philippe Dessen) is a collection of resources on genes, chromosomes anomalies, leukemias, solid tumours, and cancer-prone diseases. The project is accessible through Internet and is made of encyclopedic-style files, as well as traditional overviews, links towards websites and databases devoted to cancer and/or genetics, case reports in haematology. It also encompasses teaching items in various languages.[1]


Starting first from cytogenetics in the nineteens, the Atlas now combines different types of knowledge in a single web site: genes and their function, cell biology (ex: Apoptosis) [2], pathological data, diseases and their clinical implications, cytogenetics, but also medical genetics, with hereditary disorders associated with an increased risk of cancer. This gives a wider and more global view of cancer genetics, while these data are usually dispersed. [3] It includes a large iconography of about 35,000 images. More data is available from the site of the association in charge of the Atlas. [4].


In 2017, it contains review articles on 1,500 genes, 700 papers on leukemias, 220 on solid tumors, and 110 on hereditay disease with a cancer-prone condition and 110 "Deep Insights" on related subjects, 40,000 internal links and 730,000 external links. More than 3,300 authors have/are contributing.[5] It includes an iconography of about 35,000 images.

The Atlas is part of the genome project and participates in research on cancer epidemiology. The Atlas is accessed by: 1- researchers in cytogenetics, molecular biology, cell biology; 2- clinicians, haematologists, cytogeneticists, pathologists, from the university hospitals, indeed, but also from general hospitals where the Atlas is one of the rare free resources. Junior doctors in haematology or oncology, are also most receptive to the Atlas that they see as a training and educational tool; 3-Students in medicine and life sciences.[6]


The Atlas is financially supported by scientific societies, charities and individual donations.

See also

References

  1. ↑ "Atlas of Genetics and Cytogenetics in Oncology and Haematology, updated". Nucleic Acids Res. 29 (1): 303–4. January 2001. doi:10.1093/nar/29.1.303. PMC 29834. PMID 11125120.
  2. ↑ "<Apoptosis>". atlasgeneticsoncology.org.
  3. ↑ "Chromosomes in Cancer - Argument". chromosomesincancer.org/en.
  4. ↑ "Chromosomes in Cancer - Homepage". chromosomesincancer.org/en.
  5. ↑ "Atlas_status". atlasgeneticsoncology.org.
  6. ↑ "<GeneralBrainTumorHereditary>". www.pedsoncologyeducation.com.

Sources

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