Arnold J. Levine

Arnold J. Levine
8th President of Rockefeller University
In office
1998–2002
Preceded by Torsten Wiesel
Succeeded by Paul Nurse
Personal details
Born July 30, 1939 (1939-07-30) (age 79)
Brooklyn, New York
Nationality American
Alma mater Binghamton University
University of Pennsylvania
California Institute of Technology
Known for p53 tumor suppressor protein
Awards Ciba-Drew Award (1995)
Louisa Gross Horwitz Prize for Biology or Biochemistry (1998)
Charles S. Mott Prize (1999)
Keio Medical Science Prize (2000)
Albany Medical Center Prize in Medicine and Biomedical Research (2001)
Scientific career
Fields Molecular biology/Molecular virology/Molecular genetics
Thesis A study of the role of adenovirus structural proteins in the cessation of host cell biosynthetic functions (1966)
Doctoral advisor Harold S. Ginsberg

Arnold J. Levine (born 1939), is an American Molecular biologist. He was awarded the 1998 Louisa Gross Horwitz Prize for Biology or Biochemistry and was the first recipient of the Albany Medical Center Prize in Medicine and Biomedical Research in 2001 for his discovery of the tumor suppressor protein p53.[1]

He is currently Professor of Systems Biology at the Institute for Advanced Study in Princeton New Jersey.[2]

Career

Levine received his Ph.D. from the University of Pennsylvania in 1966.[3]

Levine discovered, with several colleagues, the p53 tumor suppressor gene in 1979, a protein involved in cell cycle regulation, and one of the most frequently mutated genes in human cancer, in work done as a professor in the biochemistry department at Princeton University. In 1979 Levine moved to become Chairman of the Department of Microbiology at Stony Brook School of Medicine before moving back to Princeton in 1984.

In 1998 Levine became the Robert and Harriet Heilbrunn Professor of Cancer Biology and President of Rockefeller University. In 2002, Levine resigned the presidency following allegations that he had an inappropriate sexual encounter with a female graduate student, while both were intoxicated. According to the woman involved, the encounter was consensual and blown out of proportion.[4][5][6]

In 2002 he moved to the Robert Wood Johnson Medical School and in 2004 added a joint appointment as Professor at the Institute for Advanced Study.

Award and honors

In addition to the Louisa Gross Horwitz Prize (Columbia University) and Albany Prize Levine has received numerous awards and honors. He was elected a Member of the U.S. National Academy of Sciences in 1991,[7] and a Member of the Institute of Medicine in 1995.[8] He won the Ciba-Drew Award in 1995. The importance of p53 in cancer biology led to a number of cancer-related awards, including the Bristol-Myers Squibb Award for Distinguished Achievement in Cancer Research (1994), the Charles S. Mott Prize from the General Motors Cancer Research Foundation (1999), the Keio Medical Science Prize (2000).[9]

See also

References

  1. ↑ Altman, Lawrence K. (March 15, 2001), "Scientist Wins Prize for Work on Cancer Gene", New York Times .
  2. ↑ Faculty profile, Institute for Advanced Study, retrieved 2011-05-12.
  3. ↑ Levine, Arnold Jay (1966). A study of the role of adenovirus structural proteins in the cessation of host cell biosynthetic functions (Ph.D.). University of Pennsylvania. OCLC 244998251 – via ProQuest. (Subscription required (help)).
  4. ↑ Arenson, Karen W. (February 11, 2002), "Amid Inquiry, President of Rockefeller U. Resigns", New York Times .
  5. ↑ Check, Erika (14 February 2002). "Rockefeller head quits as scandal looms". Nature. 415 (6873): 721–721. doi:10.1038/415721a.
  6. ↑ KISSING COED’S TALE – SMOOCH FOR SEXY PREXY ALL ‘INNOCENT’
  7. ↑ "NAS Membership Directory". U.S. National Academy of Sciences. Retrieved December 4, 2011. Search for Arnold Levine.
  8. ↑ "IOM Membership Directory - Arnold Levine". Institute of Medicine. Retrieved December 4, 2011.
  9. ↑ "The Keio Medical Science Prize Laureates". Keio University. Retrieved December 4, 2011.
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