Ameltolide

Ameltolide
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
Formula C15H16N2O
Molar mass 240.300 g/mol
3D model (JSmol)

Ameltolide, a 4-aminobenzamide derivative, is an experimental anticonvulsant agent, effective at inhibiting seizures in animal models.[1] It is non-toxic at dosing levels and no undesirable side effects are attributable to its application.[2]

References

  1. Robertson, David W.; Beedle, E. E.; Krushinski, Joseph H.; Lawson, Ronald R.; Parli, C. John; Potts, Brian; Leander, J. David (1991). "Synthesis and pharmacological evaluation of a major metabolite of ameltolide, a potent anticonvulsant". Journal of Medicinal Chemistry. 34 (4): 1253–7. doi:10.1021/jm00108a003. PMID 2016702.
  2. Higdon, Gary L.; McKinley, Edmund R.; Markham, Janet K. (1991). "Ameltolide. I: Developmental toxicology studies of a novel anticonvulsant". Teratology. 44 (1): 37–44. doi:10.1002/tera.1420440107. PMID 1957261.


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