Alimentary toxic aleukia

Alimentary toxic aleukia

Alimentary toxic aleukia, or aleukia, is a mycotoxin-induced condition characterized by nausea, vomiting, diarrhea, leukopenia (aleukia), hemorrhaging, skin inflammation, and sometimes death.[1] Alimentary toxic aleukia almost always refers to the human condition associated with presence of T2 Toxin.

History

Alimentary toxic aleukia was first characterized in the early 19th century after affecting a large population in the Orenburg district of the former U.S.S.R. during World War II. The sick people had eaten overwintered grain colonized with Fusarium sporotrichioides and Fusarium poae.[2]

References

  1. Lutsky, II; Mor, N. "Alimentary toxic aleukia (septic angina, endemic panmyelotoxicosis, alimentary hemorrhagic aleukia): t-2 toxin-induced intoxication of cats". Am J Pathol. 104: 189–91. PMC 1903757. PMID 6973281.
  2. Bennett, JW; Klich, M (July 2003). "Mycotoxins". Clin. Microbiol. Rev. 16: 497–516. doi:10.1128/cmr.16.3.497-516.2003. PMC 164220. PMID 12857779.


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