Agnes Ullmann

Agnes Ullmann (b. 1928 [1] in Romania) is a French microbiologist.

Ullmann received her doctorate in microbiology from the University of Budapest. After a research visit to Institut Pasteur in 1958/59 working with Jacques Monod, she moved to France in 1960 with the support of Monod, who smuggled her and her husband in a Hungarian caravan [2]. With a grant from the Rockefeller Foundation she went to the laboratory of Monod at the Institut Pasteur, where she remained for the rest of her career. There she became a professor, laboratory director and in 1982 a member of the Board of Directors.

Ullmann initially dealt with the effects of antibiotics at the Institut Pasteur and was able to elucidate, inter alia, the mode of action of streptomycin (as an inhibitor of protein synthesis in bacteria). She also studied the effect of Second Messenger cAMP in the bacterial cell. [3] In 1967 she showed that cAMP the catabolite repression in the bacterium E. coli cancels. Later, she also found a factor that boosts catabolite repression (CMF).

Later, she dealt with the mode of action of the whooping cough pathogen and its toxin. She showed that the toxin increases the cAMP production in the host cell and thus disturbs their metabolism. The ability of the toxin to provide other molecules with access to the attacked host cell also helped them develop vaccines by coupling the genetically engineered whooping cough toxin with antigenic fragments that were to be immunized.

In 2002 she received the Robert Koch Medal. She is an honorary member of the Hungarian Academy of Sciences.

In 1978, with André Lwoff, she published a collection of essays by Jacques Monod and she published two anthologies in memory of him.

Since 1966 Ullmann has been a French citizen.

Works

  • Editor: Origins of Molecular Biology - a tribute to Jacques Monod , [D. American Society for Microbiology]], Washington D.C., 2003 (French original 1980)
  • Editor with Ernesto Quagliarello, Giorgio Bernardi From Enzyme Adaptation to Natural Philosophy: Heritage from Jacques Monod , Elsevier 1987 (Conference in Trani 1986)
  • Editor with Antoine Danchin, Francis Gasser (Pasteur Institute): Régulation de l'expression génétique: rôle de l 'AMP cyclique' ', Paris, Hermann 1986

References

  1. ↑ According to Ärzteblatt, 2002, she was 74 years old
  2. ↑ website from Sean B. Carroll to his book about Monod, Brave Genius, with photo from Ullmann
  3. ↑ Template:Web Archive

Template:Standards data

Ullmann, Agnes
Born around 1928
Romania
Occupation french microbiologist
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