Actino-pnp RNA motif
| Actino-pnp RNA | |
|---|---|
 Consensus secondary structure of Actino-pnp RNAs | |
| Identifiers | |
| Symbol | Actino-pnp |
| Rfam | RF01688 |
| Other data | |
| Domain(s) | Bacteria |
| SO | 0005836 |
| PDB structures | PDBe |
The Actino-pnp RNA motif is a conserved structure found in actinobacteria that is apparently in the 5' untranslated regions of genes predicted to encode exoribonucleases.[1] The RNA element's function is likely analogous to an RNA structure found upstream of polynucleotide phosphorylase genes in E. coli and related enterobacteria.[2] In this latter system, the polynucleotide phosphorlyase gene regulates its own expression levels by a feedback mechanism that involves its activity upon the RNA structure. However, the E. coli RNA appears to be structurally unrelated to the Actino-pnp motif.
References
- ↑ Weinberg, Zasha; Wang, Joy X.; Bogue, Jarrod; Yang, Jingying; Corbino, Keith; Moy, Ryan H.; Breaker, Ronald R. (2010). "Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes". Genome Biology. 11 (3): R31. doi:10.1186/gb-2010-11-3-r31. PMC 2864571. PMID 20230605.
- ↑ Jarrige, Anne-Charlotte; Mathy, Nathalie; Portier, Claude (2001). "PNPase autocontrols its expression by degrading a double-stranded structure in the pnp mRNA leader". The EMBO Journal. 20 (23): 6845–6855. doi:10.1093/emboj/20.23.6845. PMC 125756. PMID 11726520.
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