ATF7IP

ATF7IP
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesATF7IP, AM, ATF-IP, MCAF, MCAF1, p621, activating transcription factor 7 interacting protein
External IDsMGI: 1858965 HomoloGene: 10051 GeneCards: ATF7IP
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12p13.1Start14,365,632 bp[1]
End14,502,935 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

55729

54343

Ensembl

ENSG00000171681

ENSMUSG00000030213

UniProt

Q6VMQ6

Q7TT18

RefSeq (mRNA)

NM_001286514
NM_001286515
NM_018179
NM_181352

NM_019426

RefSeq (protein)

NP_001273443
NP_001273444
NP_060649
NP_851997
NP_060649.3

NP_062299

Location (UCSC)Chr 12: 14.37 – 14.5 MbChr 6: 136.51 – 136.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Activating transcription factor 7-interacting protein 1 is a protein that in humans is encoded by the ATF7IP gene.[5][6][7]

Interactions

ATF7IP has been shown to interact with MBD1.[8]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000171681 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030213 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. Gunther M, Laithier M, Brison O (Dec 2000). "A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening". Mol Cell Biochem. 210 (1–2): 131–42. doi:10.1023/A:1007177623283. PMID 10976766.
  6. De Graeve F, Bahr A, Chatton B, Kedinger C (Jun 2000). "A murine ATFa-associated factor with transcriptional repressing activity". Oncogene. 19 (14): 1807–19. doi:10.1038/sj.onc.1203492. PMID 10777215.
  7. "Entrez Gene: ATF7IP activating transcription factor 7 interacting protein".
  8. Fujita, Naoyuki; Watanabe Sugiko; Ichimura Takaya; Ohkuma Yoshiaki; Chiba Tsutomu; Saya Hideyuki; Nakao Mitsuyoshi (Apr 2003). "MCAF Mediates MBD1-Dependent Transcriptional Repression". Mol. Cell. Biol. United States. 23 (8): 2834–43. doi:10.1128/MCB.23.8.2834-2843.2003. ISSN 0270-7306. PMC 152570. PMID 12665582.

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Yamada K, Kawata H, Shou Z, et al. (2003). "Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3". Biochem. J. 373 (Pt 1): 167–78. doi:10.1042/BJ20021866. PMC 1223464. PMID 12659632.
  • Fujita N, Watanabe S, Ichimura T, et al. (2003). "MCAF Mediates MBD1-Dependent Transcriptional Repression". Mol. Cell. Biol. 23 (8): 2834–43. doi:10.1128/MCB.23.8.2834-2843.2003. PMC 152570. PMID 12665582.
  • Morris JA, Kandpal G, Ma L, Austin CP (2004). "DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation". Hum. Mol. Genet. 12 (13): 1591–608. doi:10.1093/hmg/ddg162. PMID 12812986.
  • Wang H, An W, Cao R, et al. (2003). "mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression". Mol. Cell. 12 (2): 475–87. doi:10.1016/j.molcel.2003.08.007. PMID 14536086.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ichimura T, Watanabe S, Sakamoto Y, et al. (2005). "Transcriptional repression and heterochromatin formation by MBD1 and MCAF/AM family proteins". J. Biol. Chem. 280 (14): 13928–35. doi:10.1074/jbc.M413654200. PMID 15691849.
  • Chang LK, Chung JY, Hong YR, et al. (2005). "Activation of Sp1-mediated transcription by Rta of Epstein–Barr virus via an interaction with MCAF1". Nucleic Acids Res. 33 (20): 6528–39. doi:10.1093/nar/gki956. PMC 1298921. PMID 16314315.
  • Uchimura Y, Ichimura T, Uwada J, et al. (2006). "Involvement of SUMO modification in MBD1- and MCAF1-mediated heterochromatin formation". J. Biol. Chem. 281 (32): 23180–90. doi:10.1074/jbc.M602280200. PMID 16757475.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.


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