ARL8A

ARL8A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1ZD9, 2H18, 4ILE
Identifiers
Aliases	ARL8A, ARL10B, GIE2, ADP ribosylation factor like GTPase 8A
External IDs	MGI: 1915974 HomoloGene: 23600 GeneCards: ARL8A
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	202,144,743 bp[1]
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)[2]
End	135,156,269 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• nucleotide binding; • alpha-tubulin binding; • GTP binding; • protein binding; • beta-tubulin binding; • GTPase activity;
Cellular component	• cytoplasm; • spindle midzone; • lysosomal membrane; • endosome; • lysosome; • midbody; • extracellular exosome; • intracellular; • membrane; • late endosome membrane; • plasma membrane; • azurophil granule membrane; • ficolin-1-rich granule membrane;
Biological process	• cell division; • small GTPase mediated signal transduction; • cell cycle; • chromosome segregation; • neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	127829
	68724
	ENSG00000143862
	ENSMUSG00000026426
	Q96BM9
	Q8VEH3
	NM_138795; NM_001256129
	NM_026823
	NP_001243058; NP_620150
	NP_081099
	Wikidata
View/Edit Human	View/Edit Mouse

ADP-ribosylation factor-like protein 8A is a protein that in humans is encoded by the ARL8A gene.^[5]^[6]

References

Human ARL8A genome location and ARL8A gene details page in the UCSC Genome Browser.

Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Hofmann I, Munro S (2006). "An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility". J. Cell Sci. 119 (Pt 8): 1494–503. doi:10.1242/jcs.02958. PMID 16537643.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Okai T, Araki Y, Tada M, et al. (2005). "Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation". J. Cell Sci. 117 (Pt 20): 4705–15. doi:10.1242/jcs.01347. PMID 15331635.
Secombe J, Parkhurst SM (2004). "Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein". J. Biol. Chem. 279 (17): 17126–33. doi:10.1074/jbc.M310097200. PMID 14871887.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

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