ANAPC11

ANAPC11
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesANAPC11, APC11, Apc11p, HSPC214, anaphase promoting complex subunit 11
External IDsMGI: 1913406 HomoloGene: 41136 GeneCards: ANAPC11
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17q25.3Start81,890,790 bp[1]
End81,900,991 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

51529

66156

Ensembl

ENSG00000141552

ENSMUSG00000025135

UniProt

Q9NYG5

Q9CPX9

RefSeq (mRNA)

NM_001038230
NM_025389

RefSeq (protein)

NP_001033319
NP_079665

Location (UCSC)Chr 17: 81.89 – 81.9 MbChr 11: 120.6 – 120.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Anaphase-promoting complex subunit 11 is an enzyme that in humans is encoded by the ANAPC11 gene.[5][6]

Interactions

ANAPC11 has been shown to interact with ANAPC2[7][8] and CDC27.[5][9]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000141552 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025135 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 Gmachl M, Gieffers C, Podtelejnikov AV, Mann M, Peters JM (Sep 2000). "The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex". Proc Natl Acad Sci U S A. 97 (16): 8973–8. Bibcode:2000PNAS...97.8973G. doi:10.1073/pnas.97.16.8973. PMC 16806. PMID 10922056.
  6. ↑ "Entrez Gene: ANAPC11 APC11 anaphase promoting complex subunit 11 homolog (yeast)".
  7. ↑ Tang, Z; Li B; Bharadwaj R; Zhu H; Ozkan E; Hakala K; Deisenhofer J; Yu H (Dec 2001). "APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex". Mol. Biol. Cell. United States. 12 (12): 3839–51. doi:10.1091/mbc.12.12.3839. ISSN 1059-1524. PMC 60759. PMID 11739784.
  8. ↑ Ohta, T; Michel J J; Schottelius A J; Xiong Y (Apr 1999). "ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity". Mol. Cell. UNITED STATES. 3 (4): 535–41. doi:10.1016/S1097-2765(00)80482-7. ISSN 1097-2765. PMID 10230407.
  9. ↑ Vodermaier, Hartmut C; Gieffers, Christian; Maurer-Stroh, Sebastian; Eisenhaber, Frank; Peters, Jan-Michael (Sep 2003). "TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1". Curr. Biol. England. 13 (17): 1459–68. doi:10.1016/S0960-9822(03)00581-5. ISSN 0960-9822. PMID 12956947.

Further reading

  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Chang TS, Jeong W, Lee DY, et al. (2005). "The RING-H2-finger protein APC11 as a target of hydrogen peroxide". Free Radic. Biol. Med. 37 (4): 521–30. doi:10.1016/j.freeradbiomed.2004.05.006. PMID 15256223.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Vodermaier HC, Gieffers C, Maurer-Stroh S, et al. (2004). "TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1". Curr. Biol. 13 (17): 1459–68. doi:10.1016/S0960-9822(03)00581-5. PMID 12956947.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Tang Z, Li B, Bharadwaj R, et al. (2002). "APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex". Mol. Biol. Cell. 12 (12): 3839–51. doi:10.1091/mbc.12.12.3839. PMC 60759. PMID 11739784.
  • Chan AH, Lee SM, Chim SS, et al. (2001). "Molecular cloning and characterization of a RING-H2 finger protein, ANAPC11, the human homolog of yeast Apc11p". J. Cell. Biochem. 83 (2): 249–58. doi:10.1002/jcb.1217. PMID 11573242.
  • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
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