2-Fluorobenzoic acid

2-Fluorobenzoic acid
Names
	IUPAC name 2-Fluorobenzoic acid
	Other names o-Fluorobenzoic acid
Identifiers
CAS Number	445-29-4 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:19577 ;
ChEMBL	ChEMBL114383 ;
ChemSpider	9547 ;
KEGG	C02359 ;
PubChem CID	9935;
	InChI InChI=1S/C7H5FO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10) Key: NSTREUWFTAOOKS-UHFFFAOYSA-N;
	SMILES O=C(O)c1ccccc1F;
Properties
Chemical formula	C7H5FO2
Molar mass	140.11 g·mol−1
Melting point	126 °C (259 °F; 399 K)
log P	1.856
Acidity (pKa)	3.27
Hazards
Safety data sheet	Laboratory Chemical Safety Summary
Flash point	102 °C (216 °F; 375 K)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

2-Fluorobenzoic acid is an organic compound with the formula FC₆H₄CO₂H. It is one of three isomeric fluorobenzoic acids. Its conjugate base is 2-fluorobenzoate. The compound is an irritant.

Its metabolism has been studied extensively in the field of microbiology.^[1]^[2] Its conjugate base is part of the pathway of 2-fluorobiphenyl metabolism by Pseudomonas pseudoalcaligenes.

References

↑ Milne, G. W. A.; P. Goldman; J. L. Holtzman (1968). "The metabolism of 2-fluorobenzoic acid. Studies with ¹⁸O₂". J. Biol. Chem. 243: 5374–5376.
↑ Murphy, Cormac D.; Quirke, Shane; Balogun, Olufunmilayo (2008). "Degradation of fluorobiphenyl by Pseudomonas pseudoalcaligenesKF707". FEMS Microbiology Letters. 286 (1): 45–9. doi:10.1111/j.1574-6968.2008.01243.x. PMID 18616594.

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[1] Milne, G. W. A.; P. Goldman; J. L. Holtzman (1968). "The metabolism of 2-fluorobenzoic acid. Studies with ¹⁸O₂". J. Biol. Chem. 243: 5374–5376.

[2] Murphy, Cormac D.; Quirke, Shane; Balogun, Olufunmilayo (2008). "Degradation of fluorobiphenyl by Pseudomonas pseudoalcaligenesKF707". FEMS Microbiology Letters. 286 (1): 45–9. doi:10.1111/j.1574-6968.2008.01243.x. PMID 18616594.

2-Fluorobenzoic acid

See also

References