2,4,6-Trihydroxyacetophenone
Names | |
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Preferred IUPAC name
1-(2,4,6-Trihydroxyphenyl)ethan-1-one | |
Other names
1-(2,4,6-Trihydroxyphenyl)ethanone 2-Acetylphloroglucinol THAP Phloroacetophenone | |
Identifiers | |
3D model (JSmol) |
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.006.870 |
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Properties | |
C8H8O4 | |
Molar mass | 168.15 g·mol−1 |
Melting point | 219 to 221 °C (426 to 430 °F; 492 to 494 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
2,4,6-Trihydroxyacetophenone (THAP) is a phloroglucinol.
It has a plasma cholesterol-lowering activity in animals.[1]
It is also used as a matrix in matrix-assisted laser desorption/ionization (MALDI) for the analysis of acidic glycans and glycopeptides in negative ion mode.
References
- ↑ Charoenteeraboon, Juree; Nithipatikom, Kasem; Campbell, William B.; Piyachaturawat, Pawinee; Wilairat, Prapon; Rongnoparut, Pornpimol (2005). "Induction of human cholesterol 7α-hydroxylase in HepG2 cells by 2,4,6-trihydroxyacetophenone". European Journal of Pharmacology. 515 (1–3): 43–46. doi:10.1016/j.ejphar.2005.03.039. PMID 15896733.
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