holoprosencephaly

From Ancient Greek ὅλος (hólos, “whole”) + πρόσω (prósō, “forwards, onwards”) (referring to the prosencephalon (“forebrain”)) + ἐγκέφαλος (enképhalos, “brain”) + English -y (suffix denoting a condition), i.e. “condition of a whole (inappropriately divided) forebrain”. May be decomposed as holo- +‎ pro- +‎ -s- +‎ encephalo- +‎ -y

holoprosencephaly (countable and uncountable, plural holoprosencephalies)

1. (teratology) A congenital disorder involving insufficient division of the lobes of the brain during fetal development, resulting in skull and facial deformities ranging from minor cleft lip problems to cyclopia, in which a single eye develops where the nose would normally be.

• HPE (abbreviation)

• cyclopia

• Classifications of holoprosencephaly
  • alobar
  • semilobar
  • lobar
• Associated facial deformities
  • premaxillary agenesis
  • cyclopia
  • ethmocephaly
  • cebocephaly

• HPE (abbreviation)

• prosencephalon
• encephalon

• NINDS Holoprosencephaly Information Page at the (U.S.) National Institutes of Health