heartbreak

From heart +‎ break

• (Received Pronunciation) IPA^(key): /hɑːt.bɹeɪk/
• (US) IPA^(key): /hɑɹt.bɹeɪk/

heartbreak (countable and uncountable, plural heartbreaks)

1. overwhelming mental anguish or grief, especially that caused by loss or disappointment
   • 2012 August 5, Nathan Rabin, “TV: Review: THE SIMPSONS (CLASSIC): “I Love Lisa” (season 4, episode 15; originally aired 02/11/1993)”, in (Please provide the book title or journal name)‎:

     So while Ralph generally seems to inhabit a different, more glorious and joyful universe than everyone else here his yearning and heartbreak are eminently relateable. Ralph sometimes appears to be a magically demented sprite who has assumed the form of a boy, but he’s never been more poignantly, nakedly, movingly human than he is here.