dysmegakaryocytopoiesis

• dysmegacaryocytopoiesis

dys- +‎ megakaryocytopoiesis.

dysmegakaryocytopoiesis (uncountable)

1. (medicine) Dysfunctional megakaryocytopoiesis; defective maturation of bone marrow progenitor cells into megakaryocytes.
   • 1985, Grover C. Bagby, The Preleukemic Syndrome (Hemopoietic Dysplasia), CRC PressI Llc

     The marrow also showed megakaryocytosis and severe dysmegakaryocytopoiesis with numerous micromegakaryocytes and micromegakaryoblasts.

   • 1989, Stuart Roath, M. Corn, Current Approaches to Bone Marrow Histopathology, CRC Press (→ISBN), page 109

     In addition, dysmegakaryocytopoiesis, iron-laden macrophages, plasma cells and lymphoid infiltrates might be better identified in histologic sections.

   • 1994, John F. Foley, Julie M. Vose, James O. Armitage, Current Therapy in Cancer, W B Saunders Company (→ISBN)

     Dysmegakaryocytopoiesis may include hypolobulated, hyperlobulated, or multinucleated megakaryocytes, or a reduction in their number or size.

   • 2011, Richard A. McPherson, Matthew R. Pincus, Henry's Clinical Diagnosis and Management by Laboratory Methods, Elsevier Health Sciences (→ISBN), page 622

     Dysmegakaryocytopoiesis includes large megakaryocytes with unsegmented nuclei, micromegakaryocytes, and megakaryocytes with two or more small, unconnected nuclei. Megakaryocytes may be decreased in number.

   • 2013, Victor S. Blanchette, Vicky R. Breakey, Shoshana Revel-Vilk, SickKids Handbook of Pediatric Thrombosis and Hemostasis, Karger Medical and Scientific Publishers (→ISBN), page 31

     Moderate thrombocytopenia due to dysmegakaryocytopoiesis, platelet dysfunction, reticulocytosis, and globin synthesis imbalance resembling beta-thalassemia have been described among patients with X-linked thrombocytopenia with beta-thalassemia.

• dysmegakaryocytopoietic