codepletion

English

Etymology

co- +‎ depletion

Noun

codepletion (uncountable)

  1. (biology) The depletion of one substance in conjunction with the depletion of another.
    • 2016 March 4, “Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells”, in PLOS ONE‎, DOI:10.1371/journal.pone.0150450:
      We found that codepletion of ERG/FLI-1 resulted in inhibition of NR4A1 dependent H3K27ac at distal enhancers of all three induced genes (Fig 6D) and also strongly prevented NR4A1 dependent recruitment of p300 (Fig 6E).
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