bitopic

English

Etymology

bi +‎ -topic

Adjective

bitopic (not comparable)

  1. (biochemistry, of a protein) That links two separate domains
    • 2015 October 31, “Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity”, in PLOS ONE‎, DOI:10.1371/journal.pone.0141637:
      However, allosteric biased ligands may confer functional selectivity by exploiting the recently solved extracellular vestibule [50 ] to generate noncompetitive negative or positive allosteric modulators [51 ] or bitopic ligands [52 ].

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