Yūsuke

• 有介, "possessing/having, mediate"
• 行介, "to go, mediate"
• 由介, "reason, mediate"
• 征介, "conquer, mediate"
• 柚介, "citron, mediate"
• 愉祐, "pleasure, help"
• 裕祐, "abundant, help"
• 勇介, "courage, mediate"
• 雄介, "masculinity, mediate"

The name Yūsuke can also be written using the Japanese syllabary writing systems of hiragana and/or katakana

• Yusuke Aihara (born 1994), a Japanese professional vert skater
• Yusuke Chiba (チバ ユウスケ, born 1968), Japanese singer who formerly sang for Thee Michelle Gun Elephant and is the founder of the garage rock band The Birthday
• Yusuke Fujimoto (藤本祐介, born 1975), Japanese former heavyweight kickboxer
• Yusuke Hagihara (萩原 雄祐, 1897–1979), Japanese astronomer known for his contributions to celestial mechanics
• Yusuke Hashiba (羽柴 雄輔, 1851-1921), Japanese archaeologist
• Yusuke Hatanaka (畑中勇介, born 1985), Japanese cyclist
• Yusuke Hatano (波多野 裕介, born 1986), Japanese composer and arranger
• Yusuke Hayashi (林 勇介, born 1990), Japanese footballer
• Yusuke Higa (比嘉 祐介, born 1989), Japanese footballer who plays for the Yokohama F. Marinos
• Yusuke Hino (日野 裕介, born 1985), Japanese professional wrestler
• Yūsuke Ina (伊奈 祐介, born 1975), Japanese shogi player
• Yusuke Inuzuka (犬塚 友輔, born 1983), Japanese footballer
• Yūsuke Iseya (伊勢谷 友介, born 1976), Japanese actor
• Yusuke Kamiji (上地 雄輔, born 1979), Japanese actor, singer, and tarento
• Yusuke Kaneko (金子 祐介, born 1976), Japanese ski jumper
• Yusuke Kato (born 1986), Japanese footballer, who plays for Nakhon Ratchasima F.C. in the Thai Premier League
• Yusuke Kobori (小堀 佑介, born 1981), retired Japanese professional boxer and former WBA lightweight champion
• Yuusuke (musician) (ユウスケ, full name Yuusuke Kuniyoshi 国吉祐輔, born 1985), musician and one of the two vocalists of the hard rock band High and Mighty Color
• Yusuke Matsui (松井 佑介, born 1987), Japanese baseball player
• Yusuke Mine (born 1934), Japanese actor best known for his role on the 26-lesson TV program Let's Learn Japanese
• Yusuke Mori (森 勇介, born 1980), Japanese footballer who plays for Tokyo Verdy
• Yusuke Morozumi (両角 友佑, born 1985), Japanese curler
• Yusuke Murata (村田 雄介, born 1978), Japanese manga artist
• Yusuke Naora (直良 有祐, born 1971), Japanese video game art director and character designer at Square Enix
• Yusuke Niwai (庭井 祐輔, born 1991), Japanese rugby union player
• Yūsuke Numata (沼田 祐介, born 1968), Japanese voice actor
• Yusuke Oeda (大枝雄介, born 1935), Japanese professional Go player
• Yusuke Okada (岡田 優介, born 1984), Japanese basketball player
• Yusuke Omi (born 1946), Japanese footballer
• Yusuke Saikawa (born 1985), Japanese former soccer player
• Yusuke Sato (佐藤 悠介, born 1977), Japanese footballer
• Yusuke Shimada (島田 裕介, born 1982), Japanese footballer
• Yusuke Shimizu (志水 祐介, born 1988), Japanese water polo player
• Yusuke Suzuki (racewalker) (鈴木 雄介, born 1988), Japanese racewalker
• Yusuke Suzuki (footballer) (鈴木 祐輔, born 1982), Japanese footballer
• Yūsuke Santamaria (ユースケ・サンタマリア, real name Yūsuke Nakayama 中山 裕介, born 1971), Japanese singer and actor
• Yusuke Takahashi (高橋 悠介, born 1997), Japanese tennis player
• Yūsuke Tanaka (football forward) (田中 佑昌, born 1986), a Japanese footballer who plays for the J. League team JEF United Ichihara Chiba
• Yūsuke Tanaka (football defender) (田中 裕介, born 1986), Japanese footballer who plays for the J. League team Kawasaki Frontale
• Yusuke Tanaka (gymnast), Japanese gymnast who competed for Japan in the 2012 Summer Olympics
• Yusuke Tomoi (友井 雄亮, born 1980), Japanese actor from Hokkaidō Japan
• Yusuke Torigoe (鳥越 裕介, born 1971), Japanese baseball player
• Yusuke Toyama (遠山 雄亮, born 1979), Japanese shogi player
• Yusuke Yachi (谷内 雄亮, born 1980), Japanese race walker
• Yusuke Yada (谷田 悠介, born 1983), Japanese footballer currently playing for Kataller Toyama
• Yusuke Yamagata (山形 雄介, born 1986), Japanese footballer
• Yusuke Yamamoto (山本裕典, born 1988), Japanese actor from Aichi Japan
• Yusuke Yoshizaki (born 1981), Japanese former football player

• Yuusuke Amamiya (天宮 勇介), a character in the Super Sentai television series Choujuu Sentai Liveman
• Yusuke Godai (五代 雄介), the main character in the tokusatsu television series Kamen Rider Kuuga
• Yusuke Fujiwara (藤原 優介), a character in the anime spin-off series Yu-Gi-Oh! Duel Monsters GX
• Yusuke Urameshi (浦飯 幽助), the main character in the YuYu Hakusho anime and manga series
• Yusuke Sakamoto (坂本裕介), the main character in the 2000 film Juvenille
• Yusuke Yoshino (芳野 祐介), a character from the visual novel, manga, and anime Clannad
• Yusuke Fujisaki (藤崎 佑助), the main character of Sket Dance anime and manga
• Yusuke Makishima (巻島 裕介), a character of Yowamushi Pedal
• Yusuke Kitagawa (喜多川 祐介), a playable character from Persona 5
• Yusuke Oda, a character of Hajime no Ippo