USP19

USP19
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WH0, 4X3G
Identifiers
Aliases	USP19, ZMYND9, ubiquitin specific peptidase 19
External IDs	OMIM: 614471 MGI: 1918722 HomoloGene: 41730 GeneCards: USP19
Gene location (Human)
Chr.	Chromosome 3 (human)[1]
End	49,120,938 bp[1]
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)[2]
End	108,502,337 bp[2]
Gene ontology
Molecular function	• Hsp90 protein binding; • cysteine-type peptidase activity; • metal ion binding; • Lys48-specific deubiquitinase activity; • peptidase activity; • GO:0001948 protein binding; • thiol-dependent ubiquitin-specific protease activity; • hydrolase activity; • ubiquitin protein ligase binding; • thiol-dependent ubiquitinyl hydrolase activity;
Cellular component	• integral component of membrane; • endoplasmic reticulum membrane; • membrane; • endoplasmic reticulum; • cytosol; • cell nucleus;
Biological process	• protein K48-linked deubiquitination; • regulation of protein stability; • ubiquitin-dependent protein catabolic process; • protein stabilization; • response to endoplasmic reticulum stress; • proteolysis; • regulation of ERAD pathway; • regulation of cellular response to hypoxia; • negative regulation of skeletal muscle tissue development; • positive regulation of cell cycle process; • ubiquitin-dependent ERAD pathway; • negative regulation of proteasomal protein catabolic process; • protein deubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	10869
	71472
	ENSG00000172046
	ENSMUSG00000006676
	O94966
	Q3UJD6
NM_001199160; NM_001199161; NM_001199162; NM_006677; NM_001351098;
	NM_001351099; NM_001351100; NM_001351101; NM_001351102; NM_001351103; NM_001351104; NM_001351105; NM_001351106; NM_001351107; NM_001351108
	NM_001168371; NM_001168372; NM_001168373; NM_027804; NM_145407
NP_001186089; NP_001186090; NP_001186091; NP_006668; NP_001338027;
	NP_001338028; NP_001338029; NP_001338030; NP_001338031; NP_001338032; NP_001338033; NP_001338034; NP_001338035; NP_001338036; NP_001338037
	NP_001161843; NP_001161844; NP_001161845; NP_082080; NP_663382
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin specific peptidase 19 is a protein that in humans is encoded by the USP19 gene. [5]

References

GRCh38: Ensembl release 89: ENSG00000172046 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000006676 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Ubiquitin specific peptidase 19". Retrieved 2016-02-18.

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human Ubiquitin carboxyl-terminal hydrolase 19 (USP19)

USP19

References

External links

Further reading