UBL5

Ubiquitin-like protein 5 is a protein that in humans is encoded by the UBL5 gene.[5]

UBL5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesUBL5, HUB1, ubiquitin like 5
External IDsOMIM: 606849 MGI: 1913427 HomoloGene: 83305 GeneCards: UBL5
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19p13.2Start9,827,892 bp[1]
End9,830,115 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

59286

66177

Ensembl

ENSG00000198258

ENSMUSG00000084786

UniProt

Q9BZL1

Q9EPV8

RefSeq (mRNA)

NM_024292
NM_001048241

NM_025401
NM_001310746

RefSeq (protein)

NP_001041706
NP_077268
NP_001041706.1
NP_077268.1

NP_001297675
NP_079677
NP_001347954
NP_001347955
NP_001347956

Location (UCSC)Chr 19: 9.83 – 9.83 MbChr 9: 20.64 – 20.65 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

It has been shown that in C. elegans mitochondria treated to lower expression of certain electron transport chain proteins during the L3/L4 stage, its expression levels is higher leading to increased lifespans.[6]

Ubiquitin-like proteins (UBLs) are thought to be reversible modulators of protein function rather than protein degraders like ubiquitin (MIM 191339).[supplied by OMIM][5]

References

  1. GRCh38: Ensembl release 89: ENSG00000198258 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000084786 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: UBL5 ubiquitin-like 5".
  6. Mitochondrial Stress Signals Revise an Old Aging Theory - DOI 10.1016/j.cell.2010.12.023

Further reading

  • Overview of all the structural information available in the PDB for UniProt: Q9BZL1 (Human Ubiquitin-like protein 5) at the PDBe-KB.
  • Overview of all the structural information available in the PDB for UniProt: Q9EPV8 (Mouse Ubiquitin-like protein 5) at the PDBe-KB.



This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.