TRIP4

Activating signal cointegrator 1 is a protein that in humans is encoded by the TRIP4 gene.[5][6]

TRIP4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTRIP4, ASC-1, ASC1, HsT17391, ZC2HC5, SMABF1, thyroid hormone receptor interactor 4, MDCDC
External IDsOMIM: 604501 MGI: 1928469 HomoloGene: 9426 GeneCards: TRIP4
Gene location (Human)
Chr.Chromosome 15 (human)[1]
Band15q22.31Start64,387,748 bp[1]
End64,455,303 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9325

56404

Ensembl

ENSG00000103671

ENSMUSG00000032386

UniProt

Q15650

Q9QXN3

RefSeq (mRNA)

NM_016213
NM_001321924

NM_001170907
NM_019797
NM_001357872

RefSeq (protein)

NP_001308853
NP_057297

NP_001164378
NP_062771
NP_001344801

Location (UCSC)Chr 15: 64.39 – 64.46 MbChr 9: 65.83 – 65.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

TRIP4 has been shown to interact with Nuclear receptor coactivator 1.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000103671 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000032386 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Lee JW, Choi HS, Gyuris J, Brent R, Moore DD (July 1995). "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor". Mol Endocrinol. 9 (2): 243–54. doi:10.1210/me.9.2.243. PMID 7776974.
  6. "Entrez Gene: TRIP4 thyroid hormone receptor interactor 4".
  7. Kim HJ, Yi JY, Sung HS, Moore DD, Jhun BH, Lee YC, Lee JW (1999). "Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation". Mol. Cell. Biol. 19 (9): 6323–32. doi:10.1128/mcb.19.9.6323. PMC 84603. PMID 10454579.

Further reading


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