Streptomonospora alba

Streptomonospora alba is a halophilic species of bacteria.[1] YIM 90003(T) (=CCTCC AA001013(T)=DSM 44588(T)) is the type strain. It is closest to Streptomonospora salina. Its genome sequence was reported in 2015.[2]

Streptomonospora alba
Scientific classification
Kingdom:
Bacteria
Phylum:
Actinobacteria
Class:
Actinobacteria
Order:
Actinomycetales
Family:
Nocardiopsaceae
Genus:
Streptomonospora
Species:
Streptomonospora alba

Li et al., 2003

Description

Its aerial mycelium and substrate mycelium are well developed on most media. The aerial mycelium form short spore chains, bearing non-motile, straight to flexuous spores with wrinkled surfaces.

Metabolites

Streptomonospora alba was found to produce streptomonomicin, a lasso peptide antibiotic.[2] Streptomonomicin displayed selective antibacterial activity against bacteria of the Firmicutes phylum, especially Bacillus anthracis, while being inactive against Proteobacteria or Ascomycota.

References
  1. Li WJ, Xu P, Zhang LP, et al. (September 2003). "Streptomonospora alba sp. nov., a novel halophilic actinomycete, and emended description of the genus Streptomonospora Cui et al. 2001". International Journal of Systematic and Evolutionary Microbiology. 53 (Pt 5): 1421–5. doi:10.1099/ijs.0.02543-0. PMID 13130027. Retrieved 2013-07-24.
  2. Metelev M, Tietz JI, Melby JO, Blair PM, Zhu L, Livnat I, Severinov K, Mitchell DA (2015). "Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso peptide from an understudied halophilic actinomycete". Chemistry & Biology. 22 (2): 241–50. doi:10.1016/j.chembiol.2014.11.017. PMC 4336579. PMID 25601074.

Further reading
  • Whitman, William B., et al., eds. Bergey’s manual® of systematic bacteriology. Vol. 5. Springer, 2012.



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