Sialic acid binding ig-like lectin 15

Sialic acid binding Ig-like lectin 15 is a protein that in humans is encoded by the SIGLEC15 gene.[5]

SIGLEC15
Identifiers
AliasesSIGLEC15, CD33L3, HsT1361, SIGLEC-15, Sialic acid binding ig-like lectin 15, sialic acid binding Ig like lectin 15
External IDsOMIM: 618105 MGI: 3646642 HomoloGene: 52643 GeneCards: SIGLEC15
Gene location (Human)
Chr.Chromosome 18 (human)[1]
Band18q12.3Start45,825,675 bp[1]
End45,844,094 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

284266

620235

Ensembl

ENSG00000197046

ENSMUSG00000091055

UniProt

Q6ZMC9

A7E1W8

RefSeq (mRNA)

NM_213602

NM_001101038

RefSeq (protein)

NP_998767

NP_001094508

Location (UCSC)Chr 18: 45.83 – 45.84 MbChr 18: 78.04 – 78.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References
  1. GRCh38: Ensembl release 89: ENSG00000197046 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000091055 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Sialic acid binding Ig-like lectin 15".

Further reading
  • Takamiya R, Ohtsubo K, Takamatsu S, Taniguchi N, Angata T (February 2013). "The interaction between Siglec-15 and tumor-associated sialyl-Tn antigen enhances TGF-β secretion from monocytes/macrophages through the DAP12-Syk pathway". Glycobiology. 23 (2): 178–87. doi:10.1093/glycob/cws139. PMID 23035012.
  • Angata T, Tabuchi Y, Nakamura K, Nakamura M (August 2007). "Siglec-15: an immune system Siglec conserved throughout vertebrate evolution". Glycobiology. 17 (8): 838–46. doi:10.1093/glycob/cwm049. PMID 17483134.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.