Serine/threonine kinase 35

STK35
Identifiers
Aliases	STK35, serine/threonine kinase 35, CLIK1, STK35L1, Serine/threonine kinase 35
External IDs	OMIM: 609370 MGI: 1914583 HomoloGene: 15441 GeneCards: STK35
Gene location (Human)
Chr.	Chromosome 20 (human)[1]
End	2,177,038 bp[1]
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)[2]
End	129,832,287 bp[2]
Gene ontology
Molecular function	• transferase activity; • nucleotide binding; • protein kinase activity; • protein serine/threonine kinase activity; • ATP binding; • kinase activity;
Cellular component	• cytoplasm; • nucleolus; • cell nucleus; • nuclear body;
Biological process	• protein phosphorylation; • phosphorylation; • meiotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	140901
	67333
	ENSG00000125834
	ENSMUSG00000037885
	Q8TDR2
	Q80ZW0
	NM_080836
	NM_001038635; NM_183262
	NP_543026
	NP_001033724; NP_899085
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine kinase 35 is a protein that in humans is encoded by the STK35 gene.[5]

The protein encoded by this gene is a kinase that is predominantly found in the nucleus. However, it can interact with PDLIM1/CLP-36 in the cytoplasm and localize to actin stress fibers. The encoded protein may be a regulator of actin stress fibers in nonmuscle cells. [provided by RefSeq, Jul 2008].[5]

References

GRCh38: Ensembl release 89: ENSG00000125834 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000037885 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Serine/threonine kinase 35". Retrieved 2012-02-18.

Vallenius, T.; Mäkelä, T. P. (2002). "Clik1: A novel kinase targeted to actin stress fibers by the CLP-36 PDZ-LIM protein". Journal of Cell Science. 115 (Pt 10): 2067–2073. PMID 11973348.
Goyal, P.; Behring, A.; Kumar, A.; Siess, W. (2009). Randau, Lennart (ed.). "Identifying and Characterizing a Novel Protein Kinase STK35L1 and Deciphering Its Orthologs and Close-Homologs in Vertebrates". PLoS ONE. 4 (9): e6981. doi:10.1371/journal.pone.0006981. PMC 2737284. PMID 19756140.
Goyal, P.; Behring, A.; Kumar, A.; Siess, W. (2011). Parise, Gianni (ed.). "STK35L1 Associates with Nuclear Actin and Regulates Cell Cycle and Migration of Endothelial Cells". PLoS ONE. 6 (1): e16249. doi:10.1371/journal.pone.0016249. PMC 3024402. PMID 21283756.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000125834 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000037885 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Serine/threonine kinase 35". Retrieved 2012-02-18.

Serine/threonine kinase 35

References

Further reading