SRPX

Sushi repeat-containing protein SRPX is a protein that in humans is encoded by the SRPX gene.[5][6][7] Bioinformatics analysis suggests the SRPX protein is a peroxiredoxin.[8]

SRPX
Identifiers
AliasesSRPX, DRS, ETX1, HEL-S-83p, SRPX1, sushi repeat containing protein, X-linked, sushi repeat containing protein X-linked
External IDsOMIM: 300187 MGI: 1858306 HomoloGene: 4598 GeneCards: SRPX
Gene location (Human)
Chr.X chromosome (human)[1]
BandXp11.4Start38,149,336 bp[1]
End38,220,924 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

8406

51795

Ensembl

ENSG00000101955

ENSMUSG00000090084

UniProt

P78539

Q9R0M3

RefSeq (mRNA)

NM_006307
NM_001170750
NM_001170751
NM_001170752

NM_016911
NM_001365087

RefSeq (protein)

NP_001164221
NP_001164222
NP_001164223
NP_006298

NP_058607
NP_001352016

Location (UCSC)Chr X: 38.15 – 38.22 MbChr X: 10.04 – 10.12 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References

  1. GRCh38: Ensembl release 89: ENSG00000101955 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000090084 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Meindl A, Carvalho MR, Herrmann K, Lorenz B, Achatz H, Lorenz B, Apfelstedt-Sylla E, Wittwer B, Ross M, Meitinger T (Jul 1996). "A gene (SRPX) encoding a sushi-repeat-containing protein is deleted in patients with X-linked retinitis pigmentosa". Hum Mol Genet. 4 (12): 2339–46. doi:10.1093/hmg/4.12.2339. PMID 8634708.
  6. Dry KL, Aldred MA, Edgar AJ, Brown J, Manson FD, Ho MF, Prosser J, Hardwick LJ, Lennon AA, Thomson K, et al. (Jul 1996). "Identification of a novel gene, ETX1 from Xp21.1, a candidate gene for X-linked retintis pigmentosa (RP3)". Hum Mol Genet. 4 (12): 2347–53. doi:10.1093/hmg/4.12.2347. PMID 8634709.
  7. "Entrez Gene: SRPX sushi-repeat-containing protein, X-linked".
  8. Pawłowski K, Muszewska A, Lenart A, et al. (2010). "A widespread peroxiredoxin-like domain present in tumor suppression- and progression-implicated proteins". BMC Genomics. 11: 590. doi:10.1186/1471-2164-11-590. PMC 3091736. PMID 20964819.

Further reading


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