SOCS4
Suppressor of cytokine signaling 4 is a protein that in humans is encoded by the SOCS4 gene.[4]
Function
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
References
- GRCh38: Ensembl release 89: ENSG00000180008 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: Suppressor of cytokine signaling 4". Retrieved 2016-02-23.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
External links
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Suppressor of cytokine signaling 4 (SOCS4)
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