SIT1

Signaling threshold-regulating transmembrane adapter 1 is a protein that in humans is encoded by the SIT1 gene.[5][6][7]

SIT1
Identifiers
AliasesSIT1, SIT, SIT-R, signaling threshold regulating transmembrane adaptor 1
External IDsOMIM: 604964 MGI: 1889342 HomoloGene: 8694 GeneCards: SIT1
Gene location (Human)
Chr.Chromosome 9 (human)[1]
Band9p13.3Start35,649,295 bp[1]
End35,650,950 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

27240

54390

Ensembl

ENSG00000137078

ENSMUSG00000028460

UniProt

Q9Y3P8

Q8C503

RefSeq (mRNA)

NM_014450

NM_019436

RefSeq (protein)

NP_055265

NP_062309

Location (UCSC)Chr 9: 35.65 – 35.65 MbChr 4: 43.48 – 43.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References

  1. GRCh38: Ensembl release 89: ENSG00000137078 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000028460 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Hubener C, Mincheva A, Lichter P, Schraven B, Bruyns E (Aug 2001). "Complete sequence, genomic organization, and chromosomal localization of the human gene encoding the SHP2-interacting transmembrane adaptor protein (SIT)". Immunogenetics. 53 (4): 337–41. doi:10.1007/s002510100328. PMID 11491537.
  6. Marie-Cardine A, Kirchgessner H, Bruyns E, Shevchenko A, Mann M, Autschbach F, Ratnofsky S, Meuer S, Schraven B (May 1999). "SHP2-interacting Transmembrane Adaptor Protein (SIT), A Novel Disulfide-linked Dimer Regulating Human T Cell Activation". J Exp Med. 189 (8): 1181–94. doi:10.1084/jem.189.8.1181. PMC 2193021. PMID 10209036.
  7. "Entrez Gene: SIT1 signaling threshold regulating transmembrane adaptor 1".

Further reading


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