Roseburia hominis

Roseburia hominis is a bacterium first isolated from human feces. It is anaerobic, Gram-negative or Gram-variable, slightly curved rod-shaped and motile. The cells range in size from 0.5-1.5 to 5.0 μm. A2-183(T) (=DSM 16839(T)=NCIMB 14029(T)) is the type strain.[1]

Roseburia hominis
Scientific classification
Domain:
Bacteria
Phylum:
Firmicutes
Class:
Clostridia
Order:
Clostridiales
Family:
Lachnospiraceae
Genus:
Roseburia
Species:
R. hominis

Duncan et al. 2006
Binomial name
Roseburia hominis

It is being studied as a potential treatment for ulcerative colitis in pediatric patients ages 0 through 16 years.[2]

References
  1. Sylvia H. Duncan; Rustam I. Aminov; Karen P. Scott; Petra Louis; Thaddeus B. Stanton & Harry J. Flint (October 2006). "Proposal of Roseburia faecis sp. nov., Roseburia hominis sp. nov. and Roseburia inulinivorans sp. nov., based on isolates from human faeces". International Journal of Systematic and Evolutionary Microbiology. 56 (Pt 10): 2437–2441. doi:10.1099/ijs.0.64098-0. PMID 17012576.
  2. "Orphan Drug Designations and Approvals". Food and Drug Administration.

Further reading
  • Staley, James T., et al. "Bergey’s manual of systematic bacteriology, vol. 3."Williams and Wilkins, Baltimore, MD (1989): 2250-2251.
  • Martínez, Inés; Lattimer, James M; Hubach, Kelcie L; Case, Jennifer A; Yang, Junyi; Weber, Casey G; Louk, Julie A; Rose, Devin J; Kyureghian, Gayaneh; Peterson, Daniel A; Haub, Mark D; Walter, Jens (2012). "Gut microbiome composition is linked to whole grain-induced immunological improvements". The ISME Journal. 7 (2): 269–280. doi:10.1038/ismej.2012.104. ISSN 1751-7362. PMC 3554403. PMID 23038174.
  • Machiels, K.; Joossens, M.; Sabino, J.; De Preter, V.; Arijs, I.; Eeckhaut, V.; Ballet, V.; Claes, K.; Van Immerseel, F.; Verbeke, K.; Ferrante, M.; Verhaegen, J.; Rutgeerts, P.; Vermeire, S. (2013). "A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis". Gut. 63 (8): 1275–83. doi:10.1136/gutjnl-2013-304833. ISSN 0017-5749. PMID 24021287.


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