Replication protein A3

Replication protein A 14 kDa subunit is a protein that in humans is encoded by the RPA3 gene.[5][6]

RPA3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRPA3, REPA3, RP-A p14, replication protein A3
External IDsOMIM: 179837 MGI: 1915490 HomoloGene: 68285 GeneCards: RPA3
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7p21.3Start7,636,518 bp[1]
End7,718,607 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

6119

68240

Ensembl

ENSG00000106399

ENSMUSG00000012483

UniProt

P35244

Q9CQ71

RefSeq (mRNA)

NM_002947

NM_026632

RefSeq (protein)

NP_002938

NP_080908

Location (UCSC)Chr 7: 7.64 – 7.72 MbChr 6: 8.26 – 8.26 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

RPA3 has been shown to interact with replication protein A1[7][8] and replication protein A2.[7][8]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000106399 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000012483 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Umbricht CB, Erdile LF, Jabs EW, Kelly TJ (Mar 1993). "Cloning, overexpression, and genomic mapping of the 14-kDa subunit of human replication protein A". The Journal of Biological Chemistry. 268 (9): 6131–8. PMID 8454588.
  6. "Entrez Gene: RPA3 replication protein A3, 14kDa".
  7. Bochkareva E, Frappier L, Edwards AM, Bochkarev A (Feb 1998). "The RPA32 subunit of human replication protein A contains a single-stranded DNA-binding domain". The Journal of Biological Chemistry. 273 (7): 3932–6. doi:10.1074/jbc.273.7.3932. PMID 9461578.
  8. Bochkareva E, Korolev S, Lees-Miller SP, Bochkarev A (Apr 2002). "Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA". The EMBO Journal. 21 (7): 1855–63. doi:10.1093/emboj/21.7.1855. PMC 125950. PMID 11927569.

Further reading


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