RcsR1 small RNA
RcsR1 (rhizobial cold and salinity stress riboregulator 1) trans-acting sRNA, formerly known as SmelC587, is a stress-related riboregulator, conserved in Sinorhizobium, Rhizobium and Agrobacterium. It contains highly conserved stem-loops involved in the interaction with several target mRNAs (PhoR, MotE, anti-σE1, GntR, FgA, TrpC). In Sinorhizobium meliloti RcsR1 less conserved central region is responsible for the species-specific interaction with the 5’UTR of autoinducer synthase encoding mRNA sinI. The interaction negatively influences sinI translation.[1]
| RcsR1 sRNA | |
|---|---|
 Predicted secondary structure and sequence conservation of RcsR1 small RNA | |
| Identifiers | |
| Rfam | RF02552 |
| Other data | |
| Domain(s) | Bacteria |
| GO | 0040033,0032055 |
| SO | 0000370 |
| PDB structures | PDBe |
See also
References
- Baumgardt K, Šmídová K, Rahn H, Lochnit G, Robledo M, Evguenieva-Hackenberg E (May 2016). "The stress-related, rhizobial small RNA RcsR1 destabilizes the autoinducer synthase encoding mRNA sinI in Sinorhizobium meliloti". RNA Biology. 13 (5): 486–499. doi:10.1080/15476286.2015.1110673. PMC 4962803. PMID 26588798.
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