RUFY1

RUN and FYVE domain-containing protein 1 is a protein that in humans is encoded by the RUFY1 gene.[5][6] It is named after the RUN and FYVE domains it contains.

RUFY1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRUFY1, RABIP4, ZFYVE12, RUN and FYVE domain containing 1
External IDsOMIM: 610327 MGI: 2429762 HomoloGene: 23522 GeneCards: RUFY1
Gene location (Human)
Chr.Chromosome 5 (human)[1]
Band5q35.3Start179,550,554 bp[1]
End179,610,012 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

80230

216724

Ensembl

ENSG00000284260
ENSG00000176783

ENSMUSG00000020375

UniProt

Q96T51

Q8BIJ7

RefSeq (mRNA)

NM_001040451
NM_001040452
NM_025158

NM_172557

RefSeq (protein)

NP_001035541
NP_001035542
NP_079434

NP_766145

Location (UCSC)Chr 5: 179.55 – 179.61 MbChr 11: 50.39 – 50.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

RUFY1 has been shown to interact with BMX.[5]

References

  1. ENSG00000176783 GRCh38: Ensembl release 89: ENSG00000284260, ENSG00000176783 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000020375 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Yang J, Kim O, Wu J, Qiu Y (Aug 2002). "Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking". J. Biol. Chem. 277 (33): 30219–26. doi:10.1074/jbc.M111933200. PMID 11877430.
  6. "Entrez Gene: RUFY1 RUN and FYVE domain containing 1".

Further reading


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