RLF (gene)

RLF
Identifiers
Aliases	RLF, ZN-15L, ZNF292L, rearranged L-myc fusion, RLF zinc finger
External IDs	OMIM: 180610 MGI: 1924705 HomoloGene: 8243 GeneCards: RLF
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	40,240,921 bp[1]
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)[2]
End	121,215,084 bp[2]
Gene ontology
Molecular function	• DNA binding; • zinc ion binding; • GO:0001948 protein binding; • metal ion binding; • nucleic acid binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	• cell nucleus;
Biological process	• positive regulation of transcription, DNA-templated; • regulation of transcription, DNA-templated; • DNA integration; • chromosome organization; • transcription, DNA-templated; • positive regulation of transcription from RNA polymerase II promoter; • regulation of DNA methylation; • histone H3-K4 monomethylation;
	Sources:Amigo / QuickGO
Orthologs
	6018
	109263
	ENSG00000117000
	ENSMUSG00000049878
	Q13129
	n/a
	NM_012421
	NM_001081013; NM_001346660
	NP_036553
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein Rlf is a protein that in humans is encoded by the RLF gene.[5][6]

References

GRCh38: Ensembl release 89: ENSG00000117000 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000049878 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Makela TP, Kere J, Winqvist R, Alitalo K (Aug 1991). "Intrachromosomal rearrangements fusing L-myc and rlf in small-cell lung cancer". Mol Cell Biol. 11 (8): 4015–21. PMC 361204. PMID 1649386.
"Entrez Gene: RLF rearranged L-myc fusion".

Olsen JV; Blagoev B; Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Gregory SG; Barlow KF; McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Swick L, Kapatos G (2006). "A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions". J. Neurochem. 97 (5): 1447–55. doi:10.1111/j.1471-4159.2006.03836.x. PMC 2239266. PMID 16696853.
Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Colland F; Jacq X; Trouplin V; et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Lanigan TM; Liu A; Huang YZ; et al. (2003). "Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf". FASEB J. 17 (14): 2048–60. doi:10.1096/fj.02-1096com. hdl:2027.42/154294. PMID 14597674.
Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Shao H, Kadono-Okuda K, Finlin BS, Andres DA (1999). "Biochemical characterization of the Ras-related GTPases Rit and Rin". Arch. Biochem. Biophys. 371 (2): 207–19. doi:10.1006/abbi.1999.1448. PMID 10545207.
Mäkelä TP; Hellsten E; Vesa J; et al. (1996). "The rearranged L-myc fusion gene (RLF) encodes a Zn-15 related zinc finger protein". Oncogene. 11 (12): 2699–704. PMID 8545128.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000117000 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000049878 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1649386-5] Makela TP, Kere J, Winqvist R, Alitalo K (Aug 1991). "Intrachromosomal rearrangements fusing L-myc and rlf in small-cell lung cancer". Mol Cell Biol. 11 (8): 4015–21. PMC 361204. PMID 1649386.

[entrez-6] "Entrez Gene: RLF rearranged L-myc fusion".

RLF (gene)

References

Further reading