RCE1

CAAX prenyl protease 2 is an enzyme that in humans is encoded by the RCE1 gene.[5][6][7]

RCE1
Identifiers
AliasesRCE1, FACE2, RCE1A, RCE1B, Ras converting CAAX endopeptidase 1
External IDsOMIM: 605385 MGI: 1336895 HomoloGene: 3769 GeneCards: RCE1
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11q13.2Start66,842,835 bp[1]
End66,846,552 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

9986

19671

Ensembl

ENSG00000173653

ENSMUSG00000024889

UniProt

Q9Y256

P57791

RefSeq (mRNA)

NM_005133
NM_001032279

NM_023131

RefSeq (protein)

NP_001027450
NP_005124

NP_075620
NP_001355641
NP_001355642
NP_001355643
NP_001355644

Location (UCSC)Chr 11: 66.84 – 66.85 MbChr 19: 4.62 – 4.63 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000173653 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000024889 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Otto JC, Kim E, Young SG, Casey PJ (Apr 1999). "Cloning and characterization of a mammalian prenyl protein-specific protease". J Biol Chem. 274 (13): 8379–82. doi:10.1074/jbc.274.13.8379. PMID 10085068.
  6. Freije JM, Blay P, Pendas AM, Cadinanos J, Crespo P, Lopez-Otin C (Jul 1999). "Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins". Genomics. 58 (3): 270–80. doi:10.1006/geno.1999.5834. PMID 10373325.
  7. "Entrez Gene: RCE1 RCE1 homolog, prenyl protein peptidase (S. cerevisiae)".

Further reading


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