RAB13

RAB13
Identifiers
Aliases	RAB13, GIG4, member RAS oncogene family
External IDs	OMIM: 602672 MGI: 1927232 HomoloGene: 113882 GeneCards: RAB13
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	153,986,358 bp[1]
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)[2]
End	90,226,385 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• nucleotide binding; • protein kinase A catalytic subunit binding; • GTP binding; • GO:0001948 protein binding; • GTPase activity;
Cellular component	• recycling endosome; • endosome; • Golgi apparatus; • cell projection; • lateral plasma membrane; • membrane; • intercellular junction; • bicellular tight junction; • insulin-responsive compartment; • cell membrane; • endocytic vesicle; • recycling endosome membrane; • trans-Golgi network; • neuron projection; • extracellular exosome; • cytoplasmic vesicle; • lamellipodium; • cytosol; • cell junction; • cytoplasmic vesicle membrane;
Biological process	• trans-Golgi network to recycling endosome transport; • establishment of Sertoli cell barrier; • protein localization to cell leading edge; • endosomal transport; • bicellular tight junction assembly; • endothelial cell chemotaxis; • endocytic recycling; • cellular response to insulin stimulus; • protein kinase A signaling; • protein transport; • neuron projection development; • cortical actin cytoskeleton organization; • post-translational modification; • transport; • protein localization to plasma membrane; • intracellular protein transport; • Rab protein signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	5872
	68328
	ENSG00000143545
	ENSMUSG00000027935
	P51153
	Q9DD03
	NM_001272038; NM_002870
	NM_001293741; NM_026677
	NP_001258967; NP_002861
	NP_001280670; NP_080953
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein Rab-13 is a protein that in humans is encoded by the RAB13 gene.[5][6]

References

GRCh38: Ensembl release 89: ENSG00000143545 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000027935 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Zahraoui A, Joberty G, Arpin M, Fontaine JJ, Hellio R, Tavitian A, Louvard D (Feb 1994). "A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells". J Cell Biol. 124 (1–2): 101–15. doi:10.1083/jcb.124.1.101. PMC 2119893. PMID 8294494.
"Entrez Gene: RAB13 RAB13, member RAS oncogene family".

Joberty G, Tavitian A, Zahraoui A (1993). "Isoprenylation of Rab proteins possessing a C-terminal CaaX motif". FEBS Lett. 330 (3): 323–8. doi:10.1016/0014-5793(93)80897-4. PMID 8375503.
Leek JP, Hamlin PJ, Wilton J, Lench NJ (1998). "Assignment of the Rab13 gene (RAB13) to human chromosome band 12q13 by in situ hybridization". Cytogenet. Cell Genet. 79 (3–4): 210–1. doi:10.1159/000134724. PMID 9605854.
Marzesco AM, Galli T, Louvard D, Zahraoui A (1998). "The rod cGMP phosphodiesterase delta subunit dissociates the small GTPase Rab13 from membranes". J. Biol. Chem. 273 (35): 22340–5. doi:10.1074/jbc.273.35.22340. PMID 9712853.
Bao S, Zhu J, Garvey WT (1999). "Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects". Horm. Metab. Res. 30 (11): 656–62. doi:10.1055/s-2007-978953. PMID 9918381.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Morimoto S, Nishimura N, Terai T, et al. (2005). "Rab13 mediates the continuous endocytic recycling of occludin to the cell surface". J. Biol. Chem. 280 (3): 2220–8. doi:10.1074/jbc.M406906200. PMID 15528189.
Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000143545 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027935 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8294494-5] Zahraoui A, Joberty G, Arpin M, Fontaine JJ, Hellio R, Tavitian A, Louvard D (Feb 1994). "A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells". J Cell Biol. 124 (1–2): 101–15. doi:10.1083/jcb.124.1.101. PMC 2119893. PMID 8294494.

[entrez-6] "Entrez Gene: RAB13 RAB13, member RAS oncogene family".

RAB13

References

Further reading