Psychosine

Psychosine is a highly cytotoxic lipid that accumulates in the nervous system in the absence of galactosylceramidase.[1]

Psychosine
Names
IUPAC name
(2S,3R,4E)-2-Amino-3-hydroxy-4-octadecen-1-yl β-D-galactopyranoside
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.164.357
KEGG
Properties
C24H47NO7
Molar mass 461.640 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Chemically, it is a galactoside of sphingosine.

References

  1. Hawkins-Salsbury, J. A.; Parameswar, A. R.; Jiang, X; Schlesinger, P. H.; Bongarzone, E; Ory, D. S.; Demchenko, A. V.; Sands, M. S. (2013). "Psychosine, the cytotoxic sphingolipid that accumulates in globoid cell leukodystrophy, alters membrane architecture". The Journal of Lipid Research. 54 (12): 3303–3311. doi:10.1194/jlr.M039610. PMC 3826678. PMID 24006512.


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