Propagermanium

Propagermanium (INN), also known by a variety of other names including bis(2-carboxyethylgermanium) sesquioxide and 2-carboxyethylgermasesquioxane, is an organometallic compound of germanium[1] that is sold as an alternative medicine. It is a polymeric compound with the formula ((HOOCCH2CH2Ge)2O3)n.

Propagermanium
Names
IUPAC name
3-[(2-Carboxyethyl-oxogermyl)oxy-oxogermyl]propanoic acid
Other names
proxigermanium, Ge-132, germanium sesquioxide, 2-carboxyethylgermasesquioxane, SK-818, bis(2-carboxyethylgermanium) sesquioxide
Identifiers
3D model (JSmol)
ECHA InfoCard 100.032.533
UNII
Properties
C6H10O7Ge2
Molar mass 339.4222 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

The compound was first synthesized in 1967 at the Asai Germanium Research Institute in Japan. It is a water-soluble organogermanium compound used as raw material in health foods. The compound displays low toxicity in studies with rats. [2]

References

  1. M.P. Egorov, P.P. Gaspar (1994), Germanium: Organometallic chemistry in Encyclopedia of Inorganic Chemistry. John Wiley & Sons ISBN 0-471-93620-0
  2. Doi, Yuko; et al. (2017). "No carcinogenicity of poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132): 26-week feeding study using rasH2 mice". Fundamental Toxicological Sciences. 4 (3): 137–150. doi:10.2131/fts.4.137.
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