Plectranthus barbatus

Indian coleus
Scientific classification
Kingdom:	Plantae
Clade:	Tracheophytes
Clade:	Angiosperms
Clade:	Eudicots
Clade:	Asterids
Order:	Lamiales
Family:	Lamiaceae
Genus:	Plectranthus
Species:	P. barbatus
Binomial name
	Plectranthus barbatus; Andrews
Synonyms[1]
	List Coleus barbatus (Andrews) Benth.; Coleus coerulescens Gürke; Coleus forsskaolii (Poir.) Briq.; Coleus grandis L.H.Cramer; Coleus kilimandschari Gürke ex Engl.; Coleus penzigii Dammann ex Baker; Coleus speciosus Baker f.; Coleus vestitus Baker; Germanea forsskaolii Poir.; Majana forsskaolii (Poir.) Kuntze; Ocimum asperum Roth; Ocimum cinereum R.Br.; Orthosiphon asperus (Roth) Benth. ex Sweet; Plectranthus asper (Roth) Spreng.; Plectranthus coerulescens (Gürke) R.H.Willemse; Plectranthus comosus Sims; Plectranthus forsskaolii (Poir.) Willd. nom. illeg.; Plectranthus grandis (L.H.Cramer) R.H.Willemse; Plectranthus kilimandschari ( Gürke ex Engl.) H.I.Maass; Plectranthus monadelphus Roxb.; Plectranthus pseudobarbatus J.K.Morton; ;

Plectranthus barbatus, also known by the synonym Coleus forskohlii and vernacular names forskohlii[2] and Indian coleus, is a tropical perennial plant related to the typical coleus species. It produces forskolin, an extract useful for pharmaceutical preparations and research in cell biology.[3]

Name

The Brazilian name is boldo brasileiro (Portuguese pronunciation: [ˈbowdu bɾɐziˈlejɾu], or boldo gaúcho, as opposed to the Chilean true boldo), boldo-da-terra ([ˈbowdu dɐ ˈtɛʁɐ]), boldo-de-jardim ([ˈbowdu dʒi ʒaʁˈdʒĩ]) or tapete-de-Oxalá ([tɐˈpetʃi dʒ oʃaˈla]) (Oxalá's carpet, because of its velvety texture).

Chemistry

Chemical structure of forskolin

Herbal teas made from Plectranthus barbatus contains rosmarinic acid and also flavonoid glucuronides and diterpenoids.[4][5] The chemical constituents of Plectranthus barbatus showed activities in vitro, such as acetylcholinesterase inhibition.[3][4][5]

Forskolin, which derives its name from the former binomial name Coleus forskohlii, is a constituent of Plectranthus barbatus.[3][6]

Ayurveda

In Ayurvedic traditional medicine, Coleus has been used to treat heart diseases, spasmodic pain, painful urination and convulsions.[7]

References

"The Plant List: A Working List of All Plant Species".
"Plectranthus barbatus". Natural Resources Conservation Service PLANTS Database. USDA. Retrieved 7 October 2015.
Alasbahi, R. H.; Melzig, M. F. (2010). "Plectranthus barbatus: A review of phytochemistry, ethnobotanical uses and pharmacology - Part 1". Planta Medica. 76 (7): 653–61. doi:10.1055/s-0029-1240898. PMID 20178070.
Falé, P.L., Borges, C., Madeira, P.J.A., Ascensão, L.; et al. (2009). "Rosmarinic acid, scutellarein 4′-methyl ether 7-O-glucuronide and (16S)-coleon E are the main compounds responsible for the antiacetylcholinesterase and antioxidant activity in herbal tea of Plectranthus barbatus ("falso boldo")". Food Chem. 114 (3): 798–805. doi:10.1016/j.foodchem.2008.10.015.CS1 maint: multiple names: authors list (link)
Porfírio S, Falé PL, Madeira PJ, Florêncio MH, Ascensão L, Serralheiro ML (2010). "Antiacetylcholinesterase and antioxidant activities of Plectranthus barbatus tea, after in vitro gastrointestinal metabolism". Food Chem. 122: 179–187. doi:10.1016/j.foodchem.2010.02.044.
Pizzorno, Joseph E.; Murray, Michael T. (2012). Textbook of Natural Medicine (4th ed.). Edinburgh: Churchill Livingstone. p. 686. ISBN 9781437723335.
Dubey MP, Srimal RC, Nityanand S, et al. (1981). "Pharmacological studies on coleonol, a hypotensive diterpene from Coleus forskohlii". J Ethnopharmacol. 3 (1): 1–13. doi:10.1016/0378-8741(81)90010-6. PMID 7193263.

External links

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[1] "The Plant List: A Working List of All Plant Species".

[2] "Plectranthus barbatus". Natural Resources Conservation Service PLANTS Database. USDA. Retrieved 7 October 2015.

[planta-3] Alasbahi, R. H.; Melzig, M. F. (2010). "Plectranthus barbatus: A review of phytochemistry, ethnobotanical uses and pharmacology - Part 1". Planta Medica. 76 (7): 653–61. doi:10.1055/s-0029-1240898. PMID 20178070.

[Fale-4] Falé, P.L., Borges, C., Madeira, P.J.A., Ascensão, L.; et al. (2009). "Rosmarinic acid, scutellarein 4′-methyl ether 7-O-glucuronide and (16S)-coleon E are the main compounds responsible for the antiacetylcholinesterase and antioxidant activity in herbal tea of Plectranthus barbatus ("falso boldo")". Food Chem. 114 (3): 798–805. doi:10.1016/j.foodchem.2008.10.015.CS1 maint: multiple names: authors list (link)

[Porfirio-5] Porfírio S, Falé PL, Madeira PJ, Florêncio MH, Ascensão L, Serralheiro ML (2010). "Antiacetylcholinesterase and antioxidant activities of Plectranthus barbatus tea, after in vitro gastrointestinal metabolism". Food Chem. 122: 179–187. doi:10.1016/j.foodchem.2010.02.044.

[6] Pizzorno, Joseph E.; Murray, Michael T. (2012). Textbook of Natural Medicine (4th ed.). Edinburgh: Churchill Livingstone. p. 686. ISBN 9781437723335.

[7] Dubey MP, Srimal RC, Nityanand S, et al. (1981). "Pharmacological studies on coleonol, a hypotensive diterpene from Coleus forskohlii". J Ethnopharmacol. 3 (1): 1–13. doi:10.1016/0378-8741(81)90010-6. PMID 7193263.