Piericidin A

Piericidin A is an antibiotic agent[1]. It was discovered from Streptomyces mobaraensis. Being an inhibitor of NADH dehydrogenase, it inhibits electron transfer; its structure resembles that of the ubiquinone, therefore it competes with QB for binding sites in NADH dehydrogenase as well as Photosystem II.

Piericidin A
Names
IUPAC name
2-[(2E,5E,7E,9R,10R,11E)-10-Hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraen-1-yl]-5,6-dimethoxy-3-methyl-4(1H)-pyridinone
Other names
Piericidin A1, AR-054
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.162.726
MeSH Piericidin+A
UNII
Properties
C25H37NO4
Molar mass 415.566 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

References

  1. "MeSH Record of Piericidin A". U.S. National Library of Medicine, NIH. Retrieved 2018-05-22.
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