Ozenoxacin

Ozenoxacin (INN; trade names Ozaenex and Xepi) is a quinolone antibiotic used for the treatment of impetigo.[1] A 1% topical cream is approved for treatment of impetigo in Canada[2] and in the United States.[3]

Ozenoxacin
Clinical data
Trade namesOzanex; Xepi
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC21H21N3O3
Molar mass363.417 g·mol−1
3D model (JSmol)

Ozenoxacin is active against some bacteria that have developed resistance to currently used fluoroquinolone antibiotics.[4]

References

  1. Pubchem. "Ozenoxacin". pubchem.ncbi.nlm.nih.gov. Retrieved 2019-01-10.
  2. "Cipher Pharmaceuticals Receives Health Canada Approval of OZANEX (ozenoxacin cream 1%)" (Press release). Cipher Pharmaceuticals Inc.
  3. "Medimetriks Pharmaceuticals, Inc. Receives FDA Approval for Xepi™ (ozenoxacin) Cream, 1%, a Novel Topical Antibiotic for Impetigo" (Press release). Medimetriks Pharmaceuticals, Inc.
  4. López Y, Tato M, Espinal P, Garcia-Alonso F, Gargallo-Viola D, Cantón R, Vila J (Dec 2013). "In vitro activity of Ozenoxacin against quinolone-susceptible and quinolone-resistant gram-positive bacteria". Antimicrob Agents Chemother. 57 (12): 6389–6392. doi:10.1128/AAC.01509-13. PMC 3837899. PMID 24080666.


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