NMD3

NMD3
Identifiers
Aliases	NMD3, CGI-07, NMD3 ribosome export adaptor
External IDs	OMIM: 611021 MGI: 2140103 HomoloGene: 6127 GeneCards: NMD3
Gene location (Human)
Chr.	Chromosome 3 (human)[1]
End	161,253,532 bp[1]
Gene ontology
Molecular function	• protein binding, bridging; • RNA binding; • ribosomal large subunit binding;
Cellular component	• cell nucleus; • membrane; • nucleolus; • cytoplasm; • nucleoplasm;
Biological process	• protein transport; • ribosomal large subunit export from nucleus; • positive regulation of RNA biosynthetic process; • positive regulation of protein localization to nucleolus; • positive regulation of protein binding; • transport;
	Sources:Amigo / QuickGO
Orthologs
	51068
	97112
	ENSG00000169251
	n/a
	Q96D46
	Q99L48
	NM_015938; NM_001320227
	NM_133787
	NP_001307156; NP_057022
	NP_598548
	Wikidata
View/Edit Human	View/Edit Mouse

60S ribosomal export protein NMD3 is a protein that in humans is encoded by the NMD3 gene.[4][5][6]

Interactions

NMD3 has been shown to interact with XPO1.[7]

GRCh38: Ensembl release 89: ENSG00000169251 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
Trotta CR, Lund E, Kahan L, Johnson AW, Dahlberg JE (May 2003). "Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates". EMBO J. 22 (11): 2841–51. doi:10.1093/emboj/cdg249. PMC 156746. PMID 12773398.
"Entrez Gene: NMD3 NMD3 homolog (S. cerevisiae)".
Thomas F, Kutay U (Jun 2003). "Biogenesis and nuclear export of ribosomal subunits in higher eukaryotes depend on the CRM1 export pathway". J. Cell Sci. 116 (Pt 12): 2409–19. doi:10.1242/jcs.00464. PMID 12724356.

Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
Thomas F, Kutay U (2003). "Biogenesis and nuclear export of ribosomal subunits in higher eukaryotes depend on the CRM1 export pathway". J. Cell Sci. 116 (Pt 12): 2409–19. doi:10.1242/jcs.00464. PMID 12724356.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

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