Myb proto-oncogene like 1

MYBL1
Identifiers
Aliases	MYBL1, A-MYB, AMYB, MYB proto-oncogene like 1
External IDs	OMIM: 159405 MGI: 99925 HomoloGene: 32045 GeneCards: MYBL1
Gene location (Human)
Chr.	Chromosome 8 (human)[1]
End	66,614,247 bp[1]
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)[2]
End	9,700,209 bp[2]
Gene ontology
Molecular function	• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • DNA binding; • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific; • transcription factor activity, RNA polymerase II transcription factor recruiting; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	• cell nucleus;
Biological process	• positive regulation of transcription, DNA-templated; • regulation of transcription, DNA-templated; • transcription, DNA-templated; • positive regulation of transcription from RNA polymerase II promoter; • transcription from RNA polymerase II promoter; • mitotic cell cycle; • male meiosis I; • spermatogenesis; • negative regulation of transposition; • cell differentiation; • piRNA biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	4603
	17864
	ENSG00000185697
	ENSMUSG00000025912
	P10243
	P51960
	NM_001080416; NM_001144755; NM_001294282
	NM_001290397; NM_008651
	NP_001073885; NP_001138227; NP_001281211
	NP_001277326; NP_032677
	Wikidata
View/Edit Human	View/Edit Mouse

MYB proto-oncogene like 1 is a protein that in humans is encoded by the MYBL1 gene. [5]

References

GRCh38: Ensembl release 89: ENSG00000185697 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000025912 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: MYB proto-oncogene like 1". Retrieved 2016-11-15.

Ramkissoon LA, Horowitz PM, Craig JM, Ramkissoon SH, Rich BE, Schumacher SE, McKenna A, Lawrence MS, Bergthold G, Brastianos PK, Tabak B, Ducar MD, Van Hummelen P, MacConaill LE, Pouissant-Young T, Cho YJ, Taha H, Mahmoud M, Bowers DC, Margraf L, Tabori U, Hawkins C, Packer RJ, Hill DA, Pomeroy SL, Eberhart CG, Dunn IF, Goumnerova L, Getz G, Chan JA, Santagata S, Hahn WC, Stiles CD, Ligon AH, Kieran MW, Beroukhim R, Ligon KL (2013). "Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1". Proc. Natl. Acad. Sci. U.S.A. 110 (20): 8188–93. doi:10.1073/pnas.1300252110. PMC 3657784. PMID 23633565.

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